Results 121 to 130 of about 1,756,909 (330)

Effect of Charge on the Deposition of Electrostatically Charged Inhalable Aerosol in Lung Model [PDF]

, 2002
Inhalable drugs are widely used for treating lung diseases such as asthma, emphysema, and cystic fibrosis. The aerosol particles in these inhalable drugs may be charged electrostatically.
Grable, N., Saini, Divey, Yurteri, C. U., Mazumder, Malay K., Sims, Robert A.   +4 more
core   +3 more sources

Rhinovirus infection induces extracellular matrix protein deposition in asthmatic and nonasthmatic airway smooth muscle cells

, 2011
Kuo C, Lim S, King NJ, Johnston SL, Burgess JK, Black JL, Oliver BG. Rhinovirus infection induces extracellular matrix protein deposition in asthmatic and nonasthmatic airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 300: L951-L957, 2011.
Nicholas J. C. King, Sebastian L. Johnston, Lim, S, Burgess, JK, Oliver, BG, King, NJC, Janette K. Burgess, Brian G. Oliver, Curtis Kuo, Black, J, Sam Lim, Kuo, C, Burgess, J, Johnston, S, Oliver, B, Judith L. Black, Black, JL, King, N, Johnston, SL   +18 more
core   +1 more source

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Modeled small airways lung deposition of two fixed-dose triple therapy combinations assessed with in silico functional respiratory imaging. [PDF]

Respir Res, 2023
Usmani O, Li G, De Backer J, Sadafi H, Wu L, Marshall J.   +5 more
europepmc   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

Administration of Bacteriophages via Nebulization during Mechanical Ventilation: In Vitro Study and Lung Deposition in Macaques. [PDF]

Viruses, 2023
Le Guellec S, Pardessus J, Bodier-Montagutelli E, L'Hostis G, Dalloneau E, Piel D, Samaï HC, Guillon A, Mujic E, Guillot-Combe E, Ehrmann S, Morello E, Gabard J, Heuzé-Vourc'h N, Fevre C, Vecellio L.   +15 more
europepmc   +1 more source

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

Differential Performance and Lung Deposition of Levofloxacin with Different Nebulisers Used in Cystic Fibrosis. [PDF]

Int J Mol Sci, 2022
Schwarz C, Procaccianti C, Costa L, Brini R, Friend R, Caivano G, Sadafi H, Mussche C, Schwenck N, Hahn M, Murgia X, Bianco F.   +11 more
europepmc   +1 more source

TGF-beta enhances deposition of perlecan from COPD airway smooth muscle

, 2012
Ichimaru Y, Krimmer DI, Burgess JK, Black JL, Oliver BG. TGF-beta enhances deposition of perlecan from COPD airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 302: L325-L333, 2012. First published October 14, 2011; doi:10.1152/ajplung.00453.2010.-
Yukikazu Ichimaru, Krimmer, D, Burgess, JK, Janette K. Burgess, Krimmer, DI, Brian G. G. Oliver, Black, J, David I. Krimmer, Oliver, BGG, Burgess, J, Ichimaru, Y, Oliver, B, Judith L. Black, Black, JL   +13 more
core   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

Advanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan   +2 more
wiley   +1 more source