Results 161 to 170 of about 1,346,074 (337)

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Two Cases of Lung Disease Treated with the Emanations from Thorium Nitrate [PDF]

, 1904
Greg Sharp
openalex   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

Art. VIII.—Diseases of the lungs affecting those who work in dusty atmospheres [PDF]

, 1871
J. Alexander Ross
openalex   +1 more source

Both apolipoproteins B-48 and B-100 are synthesized and secreted by the human intestine

Journal of Lipid Research, 1990
Apolipoprotein B (apoB), an apolipoprotein associated with very low density lipoproteins and the atherogenic low density lipoproteins (LDL), directs the metabolism of lipoprotein particles in plasma by interacting with the LDL receptor.
JM Hoeg, DD Sviridov, GE Tennyson, SJ Demosky, Jr, MS Meng, D Bojanovski, IG Safonova, VS Repin, MB Kuberger, VN Smirnov   +9 more
doaj  

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

CMV Infection Following mRNA SARS-CoV-2 Vaccination in Solid Organ Transplant Recipients

Transplantation Direct, 2022
Shourjo Chakravorty, MD, Adam B. Cochrane, PharmD, MPH, Mitchell A. Psotka, MD, PhD, Anil Regmi, MD, Lauren Marinak, NP, Amy Thatcher, NP, Oksana A. Shlobin, MD, A. Whitney Brown, MD, Christopher S. King, MD, FCCP, Kareem Ahmad, MD, Vikramjit Khangoora, MD, Anju Singhal, MD, Steven D. Nathan, MD, FCCP, Shambhu Aryal, MD, FCCP   +13 more
doaj   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

A Histological Study of the Lungs in 52 Cases of Chronic Beryllium Disease

, 1958
W. J. Williams
openalex   +1 more source

Antiseptic Treatment of Lung-Diseases [PDF]

, 1881
John Murray
openalex   +1 more source