Results 201 to 210 of about 7,388,180 (256)

Host-pathogen pyrimidine metabolism drives cystic fibrosis lung disease. [PDF]

Nat Commun
Lohia GK, Chen YT, Chen S, Beg A, Theiller E, Cui A, Moustafa AM, Riquelme SA.   +7 more
europepmc   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Transcatheter Aortic Valve Replacement in Patients With Interstitial Lung Disease: A Cautionary Tale. [PDF]

JACC Case Rep
Schenkel R, Polycarpou A, Perlman D, Shumway S.   +3 more
europepmc   +1 more source

Configuration‐Encoded Cell Alignment by Light‐Gated Silicon Photovoltaic Microcell Arrays

Advanced Functional Materials, EarlyView.
Light‐gated silicon photovoltaic microcells convert pulsed illumination into localized electrical cues. Arranging otherwise similar microcells into four‐lobed, six‐lobed, or circular patterns directs fibroblasts into corresponding local arrangements without wired stimulation.
Yifan Tao, Ilayda Namli, Joseph Christakiran Moses, Youdi Liu, Suihong Liu, Syed Hasan Askari Rizvi, Yasar Ozer Yilmaz, Ibrahim T. Ozbolat   +7 more
wiley   +1 more source

Expanding Remote Patient Monitoring for Pre-Lung Transplant Candidates With Interstitial Lung Disease. [PDF]

Clin Transplant
Wickerson L, De Mori T, Chowdhury N, Chaparro C, Marks N, Keshavjee S, Sidhu A.   +6 more
europepmc   +1 more source

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Post-tuberculosis lung disease in treated extra-pulmonary tuberculosis. [PDF]

Am J Respir Crit Care Med
McNair E, Valawalkar S, Cox SR, Kadam A, Lele G, Gupte N, Barthwal M, Kakrani A, Mave V, Golub JE, Gupte AN.   +10 more
europepmc   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

Pulmonary Hypertension Associated With Lung Disease: An Expert Review From the Cologne Conference.

Respiration
Ulrich S, Milger K, Halank M, Klose H, Lange TJ, Leuchte HH, Nossent EJ, Seyfarth HJ, Shlobin OA, Skowasch D, Dreher M, Behr J.   +11 more
europepmc   +1 more source