Results 251 to 260 of about 1,346,074 (337)

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

Advanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie, Samin Abbaszadeh, Kik Marais, Vahideh Nosrati‐Siahmazgi, Saman Rezaei, Bo Xiao, Kamal Dua, Hélder A. Santos, Mohammad‐Ali Shahbazi   +8 more
wiley   +1 more source

Patient perspectives on educational needs in scleroderma-interstitial lung disease. [PDF]

J Scleroderma Relat Disord
Savvaides TM, Di Vitantonio TA, Edgar A, O'Beirne R, Krishnan JK, Kaner RJ, Podolanczuk AJ, Spiera R, Gordon J, Safford MM, Lakin KS, Aronson KI.   +11 more
europepmc   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Lung Disease in Sjögren's Syndrome: Insights From a Reference Center's Population. [PDF]

Cureus
Silva Araújo C, Laranjeira F, Simão de Magalhães M, Oliveira A, Vale MM, Furtado I, Farinha F, Brandão M, Valadão I.   +8 more
europepmc   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Like walking through treacle: the experience of fatigue for young people with interstitial lung disease. [PDF]

Orphanet J Rare Dis
Gilbert C, Bennett KM, Bush A, Brown C.
europepmc   +1 more source

Biomimetic Co‐delivery of Lenvatinib and FePt Nanoparticles for Enhanced Ferroptosis/Apoptosis Treatment of Hepatocellular Carcinoma

Advanced Healthcare Materials, EarlyView.
This study introduces a novel HCC treatment using poly lactic‐co‐glycolic acid (PLGA) nanoparticles encased in HCC cell membranes to co‐deliver Lenvatinib and FePt nanoparticles. This approach improves treatment efficacy by enhancing ferroptosis and apoptosis.
Feichao Xuan, Xingyang Zhao, Weiran Pang, Zirong Li, Xiangyi Yin, Weizhong Xie, Xiaojun Zeng, Liming Nie, Junying Yang, Shiying Li, Puxiang Lai, Chihua Fang   +11 more
wiley   +1 more source

Sex-specific aspects in a population of patients undergoing evaluation for interstitial lung disease with transbronchial cryobiopsy. [PDF]

Sci Rep
Reinhard J, Polke M, Buschulte K, Eichinger M, Heußel CP, Güttlein M, Michels-Zetsche JD, Wielpütz MO, Kahnert K, Kontogianni K, Klotz LV, Allgäuer M, Herth FJ, Eberhardt R, Kreuter M, Trudzinski FC.   +15 more
europepmc   +1 more source

A Comparison of the Mechanical Properties of ECM Components and Synthetic Self‐Assembling Peptides

Advanced Healthcare Materials, EarlyView.
Self‐assembling peptide hydrogels are increasingly utilized in biomedical applications. The authors review the key mechanical properties of these structures across multiple size scales and compare them to that of native extracellular matrix components, which are found to display a much wider range of structural attributes.
Alex Hartley, Philip Michael Williams, Alvaro Mata   +2 more
wiley   +1 more source

Review of the Diagnosis and Management of Pulmonary Hypertension Associated with Interstitial Lung Disease (ILD-PH). [PDF]

J Clin Med
Kattih Z, Kim HC, Aryal S, Nathan SD.
europepmc   +1 more source