Results 261 to 270 of about 2,421,996 (355)

Developing Biomaterial-Based mRNA Delivery System for Lung Disease Treatment. [PDF]

Adv Sci (Weinh)
Gu Q, Xue H, Liu Z, Rao J, Zeng L, Zhang C, Lei L, Shi L.   +7 more
europepmc   +1 more source

Imaging of Lipid Droplets in Living Cells and Mice with Metabolic Dysfunction‐Associated Steatotic Liver Disease via a Galactose‐Modified Supramolecular Near‐Infrared Fluorescent Glycoprobe

Advanced Functional Materials, EarlyView.
A galactose‐modified supramolecular near‐infrared (NIR) glycoprobe, TCF‐FBN@Gal‐BSA, enables targeted delivery to the liver through the asialoglycoprotein receptor (ASGPR) and facilitates liver‐targeting fluorescence visualization of lipid droplets (LDs) in metabolic dysfunction‐associated steatotic liver disease (MASLD) mice.
Han‐Min Wang, Lei Dong, Qiu‐Lian Hao, Lu‐Lu Sun, Xin‐Rong Li, Yu‐Wei Yuan, Ming‐Ye Tang, Jin Gong, Yi Zang, Jia Li, Tony D. James, Xiao‐Peng He, Hai‐Hao Han   +12 more
wiley   +1 more source

Emerging role of the TCA cycle and its metabolites in lung disease. [PDF]

Front Physiol
Lu X, Zhang A, Wang H, Xu X, Chen L, Luo L.   +5 more
europepmc   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Sarcopenia in end-stage lung disease patients: a systematic review and meta-analysis. [PDF]

Front Med (Lausanne)
Sheng L, Gu P, Cai L, Zhu Y, Dong M, Zeng F.   +5 more
europepmc   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

On Diseases of the Lungs

Jesús Duarte M
openalex   +1 more source

From Smog to Scar: Epigenetic Signatures of Air Pollution in Interstitial Lung Disease. [PDF]

Am J Respir Crit Care Med
Konigsberg IR, Warburton D.
europepmc   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

Advanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput, Yen‐Ting Tung, Yu‐Chi Chen, Min Jae Song, Marc Ferrer, Emily M. Lee   +5 more
wiley   +1 more source

MFAP5 as a promising biomarker for connective tissue disease-associated interstitial lung disease. [PDF]

Front Immunol
Dai Y, Zhang J, Bai X, Wu S, Chen Y, Mou D, Wang Y, Zhu Y, Liu Y.   +8 more
europepmc   +1 more source