Results 51 to 60 of about 7,388,180 (256)

Mitochondrial dysfunction in airways and quadriceps muscle of patients with chronic obstructive pulmonary disease

Respiratory Research, 2020
Background Mitochondrial damage and dysfunction have been reported in airway and quadriceps muscle cells of patients with chronic obstructive pulmonary disease (COPD).
Gulam Haji, Coen H. Wiegman, Charalambos Michaeloudes, Mehul S. Patel, Katrina Curtis, Pankaj Bhavsar, Michael I. Polkey, Ian M. Adcock, Kian Fan Chung, on behalf of the COPDMAP consortium   +9 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Union and Médecins Sans Frontières approach to operational research. [PDF]

, 2011
Operational research (OR) has become a hot topic at national meetings, international conferences and donor fora. The International Union Against Tuberculosis and Lung Disease (The Union) and Médecins Sans Frontières (MSF) Operational Centre Brussels ...
Fujiwara, P I, Berger, SD, Harries, AD, Detjen, AK, Berger, S D, Harries, A D, Detjen, A K, Bissell, K, Fussell, M, Zachariah, R, Edginton, M, Rusen, ID, Hinderaker, S G, Rusen, I D, Fujiwara, PI, Reid, T, Hinderaker, SG   +16 more
core  

Age of initiation of cigarette smoking and quit attempts among young women in India - evidence from Global Adult Tobacco Survey 2009 and 2017

Tobacco Induced Diseases, 2018
Background and challenges to implementation We estimate the age at initiation of occasional and regular cigarette smoking among young women (15-24) and estimate the likelihood of quitting smoking through age 35 years.
Pranay Lal, Mira Aghi, Deepak Sharma, Ashish Pandey   +3 more
doaj   +1 more source

Determination of The Relationship Between Severity of Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease [PDF]

Journal of Cardio-Thoracic Medicine, 2017
Introduction: Chronic obstructive pulmonary disease (COPD) patients are at increased risk of sleep-disorders. The concomitant occurrence of COPD and obstructive sleep apnea hypopnea syndrome (OSAHS) is named overlap syndrome. This study aimed to evaluate
Vahid Dehestani, Fariba Rezaeetalab, Mahnaz Amini, Davood Attaran, Leila Ghofraniha, Mohammadreza kasraei   +5 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Classification of lung disease in HRCT scans using integral geometry measures and functional data analysis [PDF]

, 2010
A framework for classification of chronic lung disease from high-resolution CT scans is presented. We use a set of features which measure the local morphology and topology of the 3D voxels within the lung parenchyma and apply functional data classification
Bhalerao, Abhir, Thönnes, Elke, Parr, David   +2 more
core   +1 more source

Obstructive lung disease does not increase lung cancer mortality among female never-smokers in Hong Kong

, 2012
SETTING: High lung cancer mortality is observed among female never-smokers in Hong Kong. OBJECTIVE: To examine the relationship between obstructive lung disease (chronic obstructive pulmonary disease and/or asthma) and lung cancer mortality by sex and ...
McGhee, S, Law, WS, Lam, TH, Chang, KC, Tam, CM, Yew, WW, Leung, CC, Tam, SY, Chan, KF   +8 more
core   +1 more source

Exploring the incidence of lung cancer in small areas across Scotland [PDF]

, 2015
Lung cancer is one of the most important causes of 'avoidable deaths' globally and is responsible for approximately 900,000 deaths per year. However, lung cancer rates tend to be higher for males than for females and the disease also varies ...
Pearce, James R,
core   +1 more source

Overnight desaturation in interstitial lung diseases: links to pulmonary vasculopathy and mortality

ERJ Open Research
Background Overnight desaturation predicts poor prognosis across interstitial lung diseases (ILDs). The aim of the present study was to investigate whether nocturnal desaturation is associated with pulmonary vasculopathy and mortality.
George A. Margaritopoulos, Athanasia Proklou, Athina Trachalaki, Diana Badenes Bonet, Maria Kokosi, Vasilis Kouranos, Felix Chua, Peter George, Elisabetta A. Renzoni, Anand Devaraj, Sujal Desai, Andrew G. Nicholson, Katerina M. Antoniou, Athol U. Wells   +13 more
doaj   +1 more source