Results 81 to 90 of about 1,504,438 (318)

A Retrospective Analysis of 2-Year Follow-Up of Patients with Incidental Findings of Sarcoidosis

Diagnostics
Introduction: Sarcoidosis is a multi-system granulomatous disease most commonly involving the lungs. It may be incidentally diagnosed during imaging studies for other conditions or non-specific symptoms.
Oluwabukola Thomas-Orogan, Shaney L. Barratt, Muhammad Zafran, Apollo Kwok, Anneliese Simons, Eoin P. Judge, Matthew Wells, Richard Daly, Charles Sharp, Abiramy Jeyabalan, Martin Plummeridge, Ladli Chandratreya, Lisa G. Spencer, Andrew R. L. Medford, Huzaifa I. Adamali   +14 more
doaj   +1 more source

Lung Biopsy in Pulmonary Veno-Occlusive Disease [PDF]

, 2001
Ivan M. Robbins, Barry W. Holcomb, James E. Loyd   +2 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Both apolipoproteins B-48 and B-100 are synthesized and secreted by the human intestine

Journal of Lipid Research, 1990
Apolipoprotein B (apoB), an apolipoprotein associated with very low density lipoproteins and the atherogenic low density lipoproteins (LDL), directs the metabolism of lipoprotein particles in plasma by interacting with the LDL receptor.
JM Hoeg, DD Sviridov, GE Tennyson, SJ Demosky, Jr, MS Meng, D Bojanovski, IG Safonova, VS Repin, MB Kuberger, VN Smirnov   +9 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Initiation of antiretroviral therapy or antiretroviral prophylaxis in pregnant women living with HIV registered in five townships of Mandalay, Myanmar: A cross sectional study

BMC Pregnancy and Childbirth, 2019
Background A series of interventions are required to prevent mother to child transmission (PMTCT) of Human Immunodeficiency Virus (HIV) starting from HIV testing of pregnant women, initiating antiretroviral therapy (ART) or antiretroviral prophylaxis to ...
Khine Wut Yee Kyaw, Aye Aye Mon, Khaing Hnin Phyo, Nang Thu Thu Kyaw, Ajay M. V. Kumar, Than Than Lwin, Zaw Zaw Aung, Thet Ko Aung, Myo Minn Oo, Thurain Htun, Sai Soe Thu Ya, Srinath Satyanarayana, Htun Nyunt Oo   +12 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Evolving Concepts in Progressive Pulmonary Fibrosis: A Clinical Update

Journal of Respiration
Progressive pulmonary fibrosis (PPF) is a clinical syndrome associated with worsening quality of life and increased mortality among patients with various interstitial lung diseases.
María Belén Noboa-Sevilla, Fernanda Hernández-González, Sandra Cuerpo-Cardeñosa, Xavier Alsina-Restoy, Nancy Pérez-Rodas, Alejandro Frino-García, Miguel Alonso-Villares, Elvis Matheus-Ramírez, Jacobo Sellarés   +8 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Building peer information exchange networks to improve child and adolescent TB care in Sub-Saharan Africa

Public Health Action
The Sub-Saharan Africa Regional Child and Adolescent TB Centre of Excellence (COE) was established in 2019 to address gaps in child and adolescent TB care in the region.
R. Mande, S.D. Berger, B. Moore, P. Thekkur, J.P. Dongo, J. Doyle, J. Harris, S.M. Graham, R.A. Dlodlo   +8 more
doaj   +1 more source