Results 101 to 110 of about 801,766 (352)

Chronic Obstructive Lung Diseases and Risk of Non-small Cell Lung Cancer in Women

Journal of Thoracic Oncology, 2009
Introduction: The link between lung cancer and chronic obstructive lung diseases (COPD) has not been well studied in women even though lung cancer and COPD account for significant and growing morbidity and mortality among women. Methods: We evaluated the
A. Schwartz, M. Cote, A. Wenzlaff, Alison L Van Dyke, Wei Chen, J. Ruckdeschel, S. Gadgeel, A. Soubani   +7 more
semanticscholar   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Generation of two human induced pluripotent stem cell lines (MHHi017-A, MHHi017-B) from a patient with primary ciliary dyskinesia carrying a homozygous mutation (c.7915C > T [p.Arg2639*]) in the DNAH5 gene

Stem Cell Research, 2020
Dynein axonemal heavy chain 5 (DNAH5) is part of a microtubule-associated protein complex found within the cilia of the lung. Mutations in the DNAH5 gene lead to impaired ciliary function and are linked to primary ciliary dyskinesia (PCD), a rare ...
Nora Drick, Julia Dahlmann, Anais Sahabian, Alexandra Haase, Gudrun Göhring, Nico Lachmann, Felix C. Ringshausen, Tobias Welte, Ulrich Martin, Ruth Olmer   +9 more
doaj  

A data analytic model to determine regional variation of asthma incidence and other chronic obstructive lung diseases in Oman

Healthcare Analytics, 2022
This study examines how asthma and other chronic obstructive lung diseases vary in different regions. Information pertaining influence of region as a proxy for the environment on asthma is not well established, yet important for healthcare, travel, and ...
Khidir Abdelbasit, Ronald Wesonga
doaj  

Assessing HyperSight iterative CBCT for dose calculation in online adaptive radiotherapy for pelvis and breast patients compared to synthetic CT

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose/objectives Recent technological advancements have increased efficiency for clinical deliverability of online‐adaptive‐radiotherapy (oART). Previous cone‐beam‐computed‐tomography (CBCT) generations lacked the ability to provide reliable Hounsfield‐units (HU), thus requiring oART workflows to rely on synthetic‐CT (sCT) images derived ...
Jingwei Duan, Joel A. Pogue, Dennis N. Stanley, Sui Shen, Natalie N. Viscariello, Carlos E. Cardenas, Richard A. Popple, Joseph Harms   +7 more
wiley   +1 more source

Different dynamics of soluble inflammatory mediators after clearance of respiratory SARS-CoV-2 versus blood-borne hepatitis C virus infections

Scientific Reports
Viral infections can be acute or chronic, with the immune system pivotal in immunopathogenesis. The potential reversibility of inflammation post-viral elimination is of current interest. This study compares the dynamics of soluble inflammatory mediators (
Antonia Zeuzem, Saumya Dileep Kumar, Carlos Oltmanns, Moana Witte, Jasmin Mischke, Nora Drick, Jan Fuge, Isabell Pink, Jan Tauwaldt, Jennifer Debarry, Thomas Illig, Heiner Wedemeyer, Benjamin Maasoumy, Yang Li, Anke R. M. Kraft, Markus Cornberg   +15 more
doaj   +1 more source

Generation of two hiPSC lines (MHHi016-A, MHHi016-B) from a primary ciliary dyskinesia patient carrying a homozygous 5 bp duplication (c.248_252dup (p.Gly85Cysfs*11)) in exon 1 of the CCNO gene

Stem Cell Research, 2020
Cyclin O (CCNO) is involved in cell cycle regulation and mutations of CCNO are linked to the rare genetic disease primary ciliary dyskinesia (PCD).
Julia Dahlmann, Anais Sahabian, Nora Drick, Alexandra Haase, Gudrun Göhring, Nico Lachmann, Felix C. Ringshausen, Tobias Welte, Ulrich Martin, Ruth Olmer   +9 more
doaj  

Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections

Nature Communications, 2018
Pulmonary infections constitute a substantial health problem worldwide. Here the authors show that phagocytes similar to primitive macrophages can be generated from human induced pluripotent stem cells, by the use of industry-compatible, stirred-tank ...
Mania Ackermann, Henning Kempf, Miriam Hetzel, Christina Hesse, Anna Rafiei Hashtchin, Kerstin Brinkert, Juliane Wilhelmine Schott, Kathrin Haake, Mark Philipp Kühnel, Silke Glage, Constanca Figueiredo, Danny Jonigk, Katherina Sewald, Axel Schambach, Sabine Wronski, Thomas Moritz, Ulrich Martin, Robert Zweigerdt, Antje Munder, Nico Lachmann   +19 more
doaj   +1 more source

Classification of COPD with Multiple Instance Learning [PDF]

, 2017
Chronic obstructive pulmonary disease (COPD) is a lung disease where early detection benefits the survival rate. COPD can be quantified by classifying patches of computed tomography images, and combining patch labels into an overall diagnosis for the image.
arxiv   +1 more source

Patient considerations in the treatment of COPD: focus on the new combination inhaler umeclidinium/vilanterol. [PDF]

, 2015
Medication adherence among patients with chronic diseases, such as COPD, may be suboptimal, and many factors contribute to this poor adherence. One major factor is the frequency of medication dosing.
Albertson, Timothy E, Harper, Richart, Murin, Susan, Sandrock, Christian   +3 more
core   +1 more source