Results 101 to 110 of about 184,952 (311)

Population-based studies on COPD : from a gender perspective [PDF]

, 2010
Men are different, women too. A concept which has long been neglected in biomedical research. Except for reproductive differences women were regarded as smaller men, clinical guidelines did not differentiate between men and women.
Schneider, Cornelia
core   +1 more source

A Molecular Shielding Strategy to Develop Low Protein Binding, Renal Clearable Pan‐Cancer Near‐Infrared Probes

Advanced Functional Materials, EarlyView.
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang, Kailin Mooney, Mingchong Dai, Morgan R. Stewart, Samantha Holland, Michael I. Henderson, Samuel Drennan, Ramon F. Barajas Jr., Jared M. Fischer, Adem Yildirim   +9 more
wiley   +1 more source

Diagnostic discordance and differential diagnoses of community-acquired pneumonia in the emergency department

BMC Emergency Medicine
Background Community-acquired pneumonia (CAP) is a common reason for presentation to the emergency department (ED), but accurate diagnosis is challenging due to overlapping and often nonspecific clinical features.
Susanne Simon, Jan Fuge, Christopher Alexander Hinze, Santiago Ewig, Tobias Welte, Torben Brod, Jessica Rademacher   +6 more
doaj   +1 more source

Obstructive lung diseases

, 2023
Obstructive lung disease is a category of lung disease characterized by difficulty exhaling air from the lungs due to airway obstruction. Obstruction can be caused by many factors, including inflammation, mucus accumulation, bronchial constriction, or damage to lung tissue.
Menekli, Tugba, Yilmaz, Feride T., Demirci, Pinar Y   +2 more
openaire   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Long-term outcomes of dupilumab therapy in severe asthma: A retrospective, multicenter, real-world study

Journal of Allergy and Clinical Immunology: Global
Background: Dupilumab is an IL-4Rα antibody approved for treatment of severe asthma. Real-world data on the continuation and cessation patterns of dupilumab and long-term treatment efficacy are scarce.
Carlo Mümmler, MD, Alexandra Lenoir, MD, Jeremias Götschke, MD, Michael Gerckens, MD, Merle Kaiser, MD, Moritz Kayser, MD, Nora Drick, MD, Hendrik Suhling, MD, Leonie Biener, MD, Carmen Pizarro, MD, Dirk Skowasch, MD, Nikolaus Kneidinger, MD, PhD, Jürgen Behr, MD, Katrin Milger, MD   +13 more
doaj   +1 more source

Quantification of dyspnoea using descriptors: development and initial testing of the Dyspnoea-12

, 2010
Rationale: Dyspnoea is a debilitating and distressing symptom that is reflected in different verbal descriptors. Evidence suggests that dyspnoea, like pain perception, consists of sensory quality and affective components.
Shuldham, C, Yorke, J., Shuldham, C., Yorke, J, Jones, PW, Jones, P. W., Moosavi, SH, Moosavi, S. H.   +7 more
core   +1 more source

COPD uncovered: an international survey on the impact of chronic obstructive pulmonary disease [COPD] on a working age population [PDF]

, 2011
Background Approximately 210 million people are estimated to have chronic obstructive pulmonary disease [COPD] worldwide. The burden of disease is known to be high, though less is known about those of a younger age.
Neil Barnes, Jones, P, Walker, S, Fletcher Monica J, Barnes, N, Buist, Sonia A., Buist, SA, Van der Molen, Thys, Barnes Neil, Paul Jones, Walsh, JW, Jenkins Christine, Van Der Molen Thys, Jane Upton, Jenkins, Christine, Walsh John W, Jenkins, C, Upton, J, Van Der Molen, T, Sonia A Buist, Fletcher, Monica J., Hutton John, Fletcher, MJ, Upton, Jane, Walker, Samantha, Taylor-Fishwick Judith, Barnes, Neil, Taylor-Fishwick, J, Jenkins, C ; https://orcid.org/, Walker Samantha, Monica J Fletcher, John Hutton, Thys Van Der Molen, Taylor-Fishwick, Judith, Samantha Walker, John W Walsh, Jones, Paul, Jones Paul, Walsh, John W., Hutton, J, Hutton, John, Buist Sonia A, Upton Jane, Judith Taylor-Fishwick, Christine Jenkins   +44 more
core   +1 more source