Results 261 to 270 of about 236,319 (284)
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Corticosteroids and obstructive lung disease
Practice Nursing, 2001In the first of two articles, Anne Baird examines the issues surrounding the use of inhaled therapy for COPD and considers the experience of Mrs White.The use of long-term oxygen therapy will be discussed in the forthcoming article.
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Airway obstruction in interstitial lung disease
Current Opinion in Pulmonary Medicine, 1997There is no question that most interstitial lung diseases result in structural alteration of the small airways as well as the alveoli. These structural changes of the airways produce airflow abnormalities that, depending on their extent and severity, are reflected in a variety of tests of pulmonary function.
Man Pyo Chung, Chong H. Rhee
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Chronic Obstructive Lung Disease
1990The term “chronic obstructive lung disease” embraces a large number of pathological conditions with the common feature of increased impedance to the air flow out of the lungs, resulting in dyspnea. The clinical, radiological, and pathophysiological features of these various (diffuse or localized) diseases are, most of the time, associated and ...
J. P. Trigaux, P. DeCoster, L. Goncette
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Protein Misfolding and Obstructive Lung Disease
Proceedings of the American Thoracic Society, 2010The endoplasmic reticulum has evolved a number of mechanisms to manage the accumulation of incorrectly folded proteins. This results in loss of function of these proteins, but occasionally, in conditions such as α-1 antitrpysin (A1AT) deficiency, the misfolded protein can acquire a toxic gain of function promoting exaggerated ER stress responses and ...
Catherine M. Greene, Noel G. McElvaney
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Ventilatory Strategies in Obstructive Lung Disease
Seminars in Respiratory and Critical Care Medicine, 2014Chronic obstructive pulmonary disease (COPD) is characterized by expiratory flow limitation (EFL) due to progressive airflow obstruction. The various mechanisms that cause EFL are central to understanding the physiopathology of COPD. At the end of expiration, dynamic inflation may occur due to incomplete emptying the lungs.
Jordi Mancebo +3 more
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Lung Transplantation for Obstructive Lung Diseases
2018Lung transplantation is commonly performed for obstructive lung diseases—most commonly chronic obstructive pulmonary disease (COPD)—and this presents unique challenges. Unlike the fibrotic conditions, obstructive lung diseases may have a more indolent course, and so timing of listing and transplantation becomes increasingly relevant. Given the variable
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Bronchodilator Therapy in Obstructive Lung Disease
Allergy and Asthma Proceedings, 1985In recent years the management of patients with obstructive lung disease has been greatly simplified by the introduction of highly selective long-acting beta adrenergic agonists, slow release theophylline preparations and locally active anticholinergic agents. The beta adrenergic compounds are the most potent and many feel that they should be the first
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MECHANICAL VENTILATION IN OBSTRUCTIVE LUNG DISEASE
Clinics in Chest Medicine, 1996This article reviews selected topics relevant to the use of mechanical ventilation in patients with severe airflow obstruction. Areas discussed include the bedside assessment of respiratory system mechanics, the ventilatory determinants of dynamic pulmonary hyperinflation, the role of controlled hypoventilation with permissive hypercapnia, and the ...
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Sputum Eosinophilia in Obstructive Lung Disease
Annals of Internal Medicine, 1971Excerpt To the editor: The recent article by Dr. Macklem and colleagues entitled "Chronic Obstructive Disease of Small Airways" (Ann Intern Med74:167-177, 1971) describes a group of patients who ar...
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CHRONIC OBSTRUCTIVE LUNG DISEASE
The Lancet, 1971J.G. Scadding, K.N.V. Palmer
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