Results 141 to 150 of about 60,558 (272)
The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley +1 more source
The 2013 Annual Report includes a review of the year, research highlights and activities across the School's three Faculties, and key facts and figures.
London School of Hygiene & Tropical Medicine
core
The Role of N6‐Methyladenosine Modification in Health and Disease
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
Pseudo-outbreak of Mycobacterium gordonae in a teaching hospital: importance of strictly following decontamination procedures and emerging issues concerning sterilization [PDF]
Aim of this study was to investigate a pseudo-outbreak of Mycobacterium gordonae analyzing isolates detected from clinical and environmental samples.
Alessia Cottarelli +10 more
core
Abstract The tapeworm, Taenia solium, is the cause of cysticercosis, a neglected zoonotic disease that poses a significant global threat to animal and public health. Data were collected between May and June 2024 using a structured, interviewer‐administered questionnaire (n = 152) comprising demographic items and sections on knowledge, attitudes, and ...
Siziwe Sibutha +2 more
wiley +1 more source
Abstract The conceptualization of mitochondria, previously restricted to their function as cellular ‘powerhouses’, has evolved to recognize their function as central coordinating hubs for the orchestration of cancer cell metabolism, signaling, and fate determination.
Woo Hyun Park
wiley +1 more source
ABSTRACT Rush Medical College implemented a new, integrated pre‐clerkship curriculum. Pharmacology was integrated with other basic sciences into a flipped, small‐group, case‐based structure. This report describes the main features of the pharmacology curriculum for pharmacology directors to have a template.
Brinda Desai Bradaric +3 more
wiley +1 more source
Foodborne trematodes: a diverse and challenging group of neglected parasites [PDF]
Blair +13 more
core +1 more source
ABSTRACT The approval requirements in new regions that do not require domestic clinical data and the clinical data evaluation of multi‐regional clinical trials (MRCTs) and foreign clinical trials (FCTs) in the Japanese approval review processes for antimicrobial medicines were explored.
Rumiko Shimazawa, Masayuki Ikeda
wiley +1 more source

