Results 141 to 150 of about 3,160,530 (245)

Trained Immunity in Childhood Vaccination

Acta Paediatrica, Volume 115, Issue 11, Page 2402-2413, November 2026.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai, Lubnaa Hossenbaccus, Eva Kaufmann   +2 more
wiley   +1 more source

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

Journal of Fish Diseases, Volume 49, Issue 11, November 2026.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon, Rebecca R. Kwabiah, Hélène Paradis, Manuel A. Soto‐Dávila, Sathees Duglas, Raja Ram Gurung, Thurka Paramanathan, Ignacio Vasquez, Shams Al‐Badoosh, John Law, Javier Santander, Mark D. Fast, Robert L. Gendron   +12 more
wiley   +1 more source

Capturing excess cause‐specific mortality during the COVID‐19 pandemic in the Netherlands using an advanced multi‐state model with relative survival

Statistica Neerlandica, Volume 80, Issue 4, November 2026.
Abstract We present a new framework to estimate excess cause‐specific mortality by integrating relative survival into a multi‐state model, motivated by the question of how vaccination and infection impacted different components of excess mortality for the older Dutch population during the first two years of the COVID‐19 pandemic in the Netherlands. The
Owen R. McWilliams, Mark G.J. de Boer, Liesbeth C. de Wreede, Eva A.S. Koster   +3 more
wiley   +1 more source

Chemoprophylaxis of Malaria : Supplement

This statement was prepared by the Parasitic Diseases Division, Bureau of Epidemiology ...

core  

Immunoregulatory mechanisms in parasitic eosinophilic lung disease: the role of IgE immune complexes and NLRC4 inflammasome. [PDF]

Front Immunol
Cao Y, Rao D, Peng Z, Chen Z, Xia Q, Xie C, Fu Y, Huang D, Zhang Z, Yao C.   +9 more
europepmc   +1 more source

From Dysbiosis to Disease: How Vaginal Microbiota Shape Group B Streptococcus Pathogenesis

ChemBioChem, Volume 27, Issue 20, 28 October 2026.
Lactobacillus crispatus plays a critical role in the vaginal microbiome. Limiting glucose shifts metabolism toward HMO consumption and amino acid metabolism. These actions enable alkali production and competition. Homeostasis, characterized by dense Lactobacilli colonization and suppression of pathogens, provides resistance to dysbiosis.
Julie A. Talbert, Steven D. Townsend
wiley   +1 more source

The multifaceted role of mesenchymal stem cells in infectious diseases: antimicrobial properties, immunomodulation and tissue repair. [PDF]

Front Immunol
Nyabi O, Temsamani F, Agalit A, El Bakkouri K, Hendi Z, Al Battah F, Vosough M, Idrissi Serhrouchni K, Najimi M.   +8 more
europepmc   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, Volume 13, Issue 57, 14 October 2026.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, Volume 13, Issue 60, 28 October 2026.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma

Advanced Science, Volume 13, Issue 58, 19 October 2026.
Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul, Alexandra Moreno Mitchell, Dean O'Neil, Yutong Luo, Khuloud T. Al‐Jamal   +4 more
wiley   +1 more source