Results 221 to 230 of about 12,137,319 (407)

Curated and harmonised transcriptomics datasets of interstitial lung diseases. [PDF]

Data Brief
Inkala S, Federico A, Serra A, Greco D.
europepmc   +2 more sources

Covid-19 disease: CT chest volume assessment using nonspecific software “Lung Density” present on “Extended Brilliance Workspace”

, 2020
Ferdinando Spanò, Matteo Arminio, Alessandro Carucci, Dario Di Luzio, Iolanda Grimaldi, Angelo Pittalis, Stefano Caprasecca, Alessandra Tortora, Silvia Lanciotti, Floriana Filannino, Paolo Ricci   +10 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

The Emerging Role of METTL3 in Lung Diseases. [PDF]

Int J Mol Sci
Dong Y, Liu Y, Marciano D, Nefzi A, Black SM, Wang T.   +5 more
europepmc   +1 more source

Treatment for systemic sclerosis-associated interstitial lung disease

, 2021
David Roofeh, Alain Lescoat, Dinesh Khanna   +2 more
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Precision Medicine Advances in Chronic Lung Diseases. [PDF]

Int J Mol Sci
Bakakos A, Tzilas V, Loukides S, Bakakos P, Karampitsakos T.   +4 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Aging and lung diseases: Unraveling mechanisms and therapeutic targets. [PDF]

Chin Med J Pulm Crit Care Med
Zhou Y, Chen G, Li X, Li X, Lin Z, Liu L, Pu D, Chen J, Chen Y, Lin Z, Zhang Z, Zhu L, Lu W, Ning W, Wang J, Ying S, Zhang J, Zhou Q, Song Y.   +18 more
europepmc   +1 more source

Diagnostic Accuracy of Chest Radiography for Detecting Fibrotic Interstitial Lung Disease

, 2022
Sahand Ghodrati, Janelle Vu Pugashetti, Michel Kadoch, Ahmadreza Ghasemiesfe, Justin M. Oldham   +4 more
openalex   +2 more sources