Results 121 to 130 of about 1,520,222 (341)

A comparison of respiratory oscillometry and spirometry in idiopathic pulmonary fibrosis: performance time, symptom burden and test–retest reliability

ERJ Open Research
Study question In large multinational patient surveys, spirometry (which requires repeated, reproducible maximal efforts) can be associated with cough, breathlessness and tiredness, particularly in those with idiopathic pulmonary fibrosis (IPF ...
Suhani Patel, Karl P. Sylvester, Zhe Wu, Serena Rhamie, Peter Dickel, Toby M. Maher, Philip L. Molyneaux, Peter M.A. Calverley, William D-C. Man   +8 more
doaj   +1 more source

Prediction and forecasting models based on patient's history and biomarkers with application to Scleroderma disease [PDF]

arXiv, 2018
This paper aims at predicting lung function values based on patients historical lung function values and serum biomarkers in Scleroderma patients. The progression of disease is measured by three lung function indexes (FVC, TLC, DLCO). Values of four biomarkers (TIMP1, P3NP, HA, NT-proBNP) are available.
arxiv  

Lung function in patients with left-to-right shunts. [PDF]

, 1967
H Davies, N Gazetopoulos
openalex   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

The application of multiple metrics in deformable image registration for target volume delineation of breast tumor bed

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Background and purpose For postoperative breast cancer patients, deformable image registration (DIR) is challenged due to the large deformations and non‐correspondence caused by tumor resection and clip insertion. To deal with it, three metrics (fiducial‐, region‐, and intensity‐based) were jointly used in DIR algorithm for improved accuracy ...
Xin Xie, Yuchun Song, Feng Ye, Hui Yan, Shulian Wang, Xinming Zhao, Jianrong Dai   +6 more
wiley   +1 more source

Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β2AR-cAMP Responsiveness in Murine Hearts

Cell Reports, 2018
Summary: Cardiomyocytes from the apex but not the base of the heart increase their contractility in response to β2-adrenoceptor (β2AR) stimulation, which may underlie the development of Takotsubo cardiomyopathy.
Peter T. Wright, Navneet K. Bhogal, Ivan Diakonov, Laura M.K. Pannell, Ruwan K. Perera, Nadja I. Bork, Sophie Schobesberger, Carla Lucarelli, Giuseppe Faggian, Anita Alvarez-Laviada, Manuela Zaccolo, Timothy J. Kamp, Ravi C. Balijepalli, Alexander R. Lyon, Sian E. Harding, Viacheslav O. Nikolaev, Julia Gorelik   +16 more
doaj  

MORTALITY IN COALWORKERS' PNEUMOCONIOSIS RELATED TO LUNG FUNCTION: A PROSPECTIVE STUDY [PDF]

, 1965
P. D. Oldham, C. E. Rossiter
openalex   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Evaluation of intrafraction couch shifts for proton treatment delivery in head‐and‐neck cancer patients: Toward optimal imaging frequency

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Treatment planning for head‐and‐neck (H&N) cancer, in particular oropharynx, nasopharynx, and paranasal sinus cases, at our center requires noncoplanar proton beams due to the complexity of the anatomy and target location. Targeting accuracy for all beams is carefully evaluated by using image guidance before delivering proton beam ...
Nrusingh C. Biswal, Dario B. Rodrigues, Weiguang Yao, Jason K. Molitoris, Matthew E. Witek, Shifeng Chen   +5 more
wiley   +1 more source

Cold plasma with zirconia nanoparticles for lung cancer via TGF-\b{eta} signaling pathway [PDF]

arXiv
Despite advancements in lung cancer therapy, the prognosis for advanced or metastatic patients remains poor, yet many patients eventually develop resistance to standard treatments leading to disease progression and poor survival. Here, we described a combination of CAP and nanoparticles (ZrO2 NPs (zirconium oxide nanoparticle) and 3Y-TZP NPs (3% mol ...
arxiv