Results 121 to 130 of about 13,666,218 (427)

Correlation of Lipopolysaccharide Endotoxin Level in Cotton Dust with the Increase of TNFα Level and the Decline of Lung Function in Cotton Spinning Factory Workers [PDF]

open access: yes, 2014
Lipopolysaccharide (LPS) endotoxin contained in cotton dust may cause airway inflammation and decline of lung function when inhaled, which eventually leads to respiratory symptoms.
Indahwati, L. (Leli)   +2 more
core   +2 more sources

Lifetime Exposure to Ambient Pollution and Lung Function in Children.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2016
RATIONALE Few studies have examined associations between exposure to air pollution and childhood lung function after implementation of strict air quality regulations in the 1990s.
M. Rice   +12 more
semanticscholar   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936 [PDF]

open access: yes, 2015
Background: The DNA methylation-based 'epigenetic clock' correlates strongly with chronological age, but it is currently unclear what drives individual differences. We examine cross-sectional and longitudinal associations between the epigenetic clock and
Corley, Janie   +17 more
core   +1 more source

Obesity: systemic and pulmonary complications, biochemical abnormalities, and impairment of lung function

open access: yesMultidisciplinary Respiratory Medicine, 2016
Obesity is currently one of the major epidemics of this millennium and affects individuals throughout the world. It causes multiple systemic complications, some of which result in severe impairment of organs and tissues.
T. Mafort, R. Rufino, C. Costa, A. Lopes
semanticscholar   +1 more source

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

U-Det: A Modified U-Net architecture with bidirectional feature network for lung nodule segmentation [PDF]

open access: yesarXiv, 2020
Early diagnosis and analysis of lung cancer involve a precise and efficient lung nodule segmentation in computed tomography (CT) images. However, the anonymous shapes, visual features, and surroundings of the nodule in the CT image pose a challenging problem to the robust segmentation of the lung nodules.
arxiv  

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Learning Permutation Invariant Representations using Memory Networks [PDF]

open access: yesarXiv, 2019
Many real-world tasks such as classification of digital histopathology images and 3D object detection involve learning from a set of instances. In these cases, only a group of instances or a set, collectively, contains meaningful information and therefore only the sets have labels, and not individual data instances.
arxiv  

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