Results 131 to 140 of about 1,734,155 (309)
Serial lung function studies in cystic fibrosis in the first 5 years of life. [PDF]
S. Godfrey, M B Mearns, G. Howlett
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This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Peripheral airways as a determinant of ventilatory function in the human lung. [PDF]
D. E. Niewoehner+2 more
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Lung function in paediatrics. Lung function testing in children
openaire +3 more sources
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Clinical application of regional lung function studies in infants and small children using 13N. [PDF]
R Ronchetti+4 more
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Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
LUNG FUNCTION AND ACID‐BASE BALANCE IN THE NEWBORN INFANT
Günter Koch
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The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
The laboratory of lung function in the follow-up of lung transplant recipients. [PDF]
Neder JA, O'Donnell DE, Berton DC.
europepmc +1 more source