Results 171 to 180 of about 1,520,222 (341)
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Forced expiratory time--its reliability as a lung function test. [PDF]
, 1975 J Macdonald, Tim Cole, Anthony Seaton
openalex +1 more source
FEBS Open Bio, EarlyView.Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano +16 more
wiley +1 more source
Functional Morphology of the Distal Lung
, 1974 Publisher Summary This chapter reviews the information concerning the form and function of the distal lung, defined as terminal bronchioles, respiratory bronchioles, and alveolar ducts, from the viewpoint of cell biology. The chapter summarizes the data produced by microscopy, electron microscopy, biochemistry, and cell and tissue culture.
openaire +3 more sources
FEBS Open Bio, EarlyView.FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source
FLOW DISTRIBUTION IN ABNORMAL LUNG AS A FUNCTION OF F1O2 [PDF]
, 1979 Inger Johansen, Jonathan L. Benumof
openalex +1 more source
FEBS Open Bio, EarlyView.Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy +14 more
wiley +1 more source
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source
Serial lung function studies in cystic fibrosis in the first 5 years of life. [PDF]
, 1978 S. Godfrey, M B Mearns, G. Howlett
openalex +1 more source
Lung function in paediatrics. Lung function testing in children
Allergologia et Immunopathologia, 2010 openaire +3 more sources