Results 191 to 200 of about 1,947,503 (351)

Particulate matter levels and children's lung function in a rural cohort near a drying saline lake. [PDF]

Environ Epidemiol
Guo F, Kamai EM, Eckel SP, Barahona DD, Olmedo L, Bejarano E, Torres C, Zuidema C, Seto E, Farzan SF, Johnston JE.   +10 more
europepmc   +1 more source

Undersized lung allograft and long-term pulmonary function after lung transplantation: analysis of Korean Organ Transplantation Registry (KOTRY) data

, 2022
Ryoung‐Eun Ko, Yong Soo Choi, Jin Gu Lee, Song Yee Kim, Young Tae Kim, Sun Mi Choi, Do Hyung Kim, Woo Hyun Cho, Kyeongman Jeon   +8 more
openalex   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Genetic Association of Mood Swings with Lung Function and Respiratory Diseases. [PDF]

J Pers Med
Ku Y, Li S, Wu D, Luo N, Gong Z, Hu B, Zhao K.   +6 more
europepmc   +1 more source

CCN1 secretion and cleavage regulate the lung epithelial cell functions after cigarette smoke

, 2014
Hyung‐Geun Moon, Sang‐Heon Kim, Jinming Gao, Taihao Quan, Zhaoping Qin, Juan C. Osorio, Iván O. Rosas, Min Wu, Yohannes Tesfaigzi, Yang Jin   +9 more
openalex   +2 more sources

Budesonide and nedocromil did not improve lung function in children with asthma [PDF]

, 2001
FM Ducharme
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Lung function assessment by electrical impedance tomography among obese patients. [PDF]

Sci Rep
Kwok WC, Touboul A, Chow WS, Chan J, Sarangi V, Yuen MMA.   +5 more
europepmc   +1 more source