Results 231 to 240 of about 4,146,103 (355)

Golgi-Targeted Viscosity Fluorescent Probe for Monitoring Acute Lung Injury. [PDF]

Chemistry
Li Y, Yang Z, Lei J, Dai Q, Li G, Xu H, Lu J, Yoon J.   +7 more
europepmc   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Acute lung injury: pathogenesis and treatment. [PDF]

J Transl Med
Liu H, Dong J, Xu C, Ni Y, Ye Z, Sun Z, Fan H, Chen Y.   +7 more
europepmc   +1 more source

Comparison of two fluid-management strategies in acute lung injury.

New England Journal of Medicine, 2006
H. Wiedemann, A. Wheeler, G. Bernard, B. Thompson, Douglas Hayden, B. deBoisblanc, A. Connors, R. D. Hite, A. Harabin   +8 more
semanticscholar   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Experimental Models of Acute Lung Injury to Study Inflammation and Pathophysiology: A Narrative Review. [PDF]

Antioxidants (Basel)
Nagato AC, Machado-Junior PA, Valenca SS, Russo RC, Bezerra FS.   +4 more
europepmc   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Cardiosphere-derived cells in the primary prevention of sepsis-induced acute lung injury in pigs. [PDF]

PLoS One
Dawkins JF, Nawaz A, Sanchez L, Sulague R, Verfaillie A, Cardenas J, Cingolani E, Lewis M, Marbán E.   +8 more
europepmc   +1 more source

Caspase-11–mediated endothelial pyroptosis underlies endotoxemia-induced lung injury

Journal of Clinical Investigation, 2017
K. Cheng, Shiqin Xiong, Zhiming Ye, Z. Hong, A. Di, K. Tsang, Xiao‐pei Gao, S. An, M. Mittal, S. Vogel, Edward A. Miao, J. Rehman, A. Malik   +12 more
semanticscholar   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source