Results 251 to 260 of about 4,146,103 (355)

Expandable Nanocomposite Shape‐Memory Hemostat for the Treatment of Noncompressible Hemorrhage

Advanced Science, EarlyView.
A nanocomposite‐coated shape memory foam rapidly expands, accelerates clotting, and reduces blood loss in vivo. Its fast volumetric expansion and strong procoagulant activity make it a promising hemostat for treating deep, noncompressible hemorrhage.
Saptarshi Biswas, Sarah E. Miller, Shounak Roy, Jeevika Thazhaiselvam, Samantha Foster, Manivannan Sivaperuman Kalairaj, Sasha M. George, Yava Jones‐Hall, Staci J. Horn, Fred J. Clubb, Taylor H. Ware, Duncan J. Maitland, Akhilesh K. Gaharwar   +12 more
wiley   +1 more source

The Extracellular Matrix and the Immune System in Acute Lung Injury: Partners in Damage and Repair. [PDF]

Biomedicines
Xie F, Sun Y, Wang J, Luo W, Zhang X, Cheng Y, Chao J.   +6 more
europepmc   +1 more source

NLRP3/ASC-mediated alveolar macrophage pyroptosis enhances HMGB1 secretion in acute lung injury induced by cardiopulmonary bypass

Laboratory Investigation, 2018
L. Hou, Zhongwei Yang, Zhankui Wang, Xiao Zhang, Yanhua Zhao, Hao Yang, Beijie Zheng, W. Tian, Shaocheng Wang, Zhengyu He, Xiangrui Wang   +10 more
semanticscholar   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Acute Lung Injury Induced by Hyperbaric Oxygen or Other External Factors, with a Focus on Exosomes. [PDF]

Int J Mol Sci
Shi J, Zhao H, Yan C, Zhu P, Zhu Q, Ding W, Wang L, Zhao Y, Wang Y, Fang Y.   +9 more
europepmc   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Siglec-F Deficiency Prevents Fibrosis after Bleomycin-induced Acute Lung Injury. [PDF]

Am J Respir Cell Mol Biol
Orlov M, Hara N, Rangarajan S, Jaramillo AM, Ye Q, Romo-Perez YM, Ngo K, NeeDell JC, Harder AQ, Jia F, Vestal B, Blumhagen RZ, Tu TH, McClendon J, McCubbrey AL, Smith BJ, Schwartz DA, Janssen WJ, Evans CM.   +18 more
europepmc   +1 more source

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

Rab43 mitigates the inflammatory response in acute lung injury via MyD88 ubiquitination. [PDF]

Sci Rep
Wang Y, Liu X, Zhu Z, Wu D, Chen Y, Gong D, Wu P, Qian H, He B, Wang G.   +9 more
europepmc   +1 more source