Results 281 to 290 of about 4,146,103 (355)

Ventilator-Associated Lung Injury: Pathophysiology, Prevention, and Emerging Therapeutic Strategies. [PDF]

Int J Mol Sci
Costa A, Sakho B, Gomez S, Khanyan B, Leybengrub P, Bergese S.   +5 more
europepmc   +1 more source

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

The CXCL12/CXCR4 Axis in Sepsis-Induced Acute Lung Injury: Mechanisms and Therapeutic Potential. [PDF]

Curr Issues Mol Biol
Luo R, Fan Q, Chen Q, Nie Z, Dan L, Xie S.   +5 more
europepmc   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Fisetin Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Targeting Myeloid Differentiation Factor 88. [PDF]

Inflammation
Jin Z, Liu X, Xie Z, Xie Y, Xu K, Zhao S, Zhou Z, Qian C, Jiang Y, Lin F, Liu Y, Chen R, Chen G, Wang Y.   +13 more
europepmc   +1 more source

Curcumin Attenuates Lipopolysaccharide-Induced Acute Lung Injury Through Anti-Inflammatory Effects in RAW Cells. [PDF]

Chonnam Med J
Li M, Bom JS, Heo J, Park CH, Kwak SH.
europepmc   +1 more source

Lactate attenuates PANoptosis and enhances ZBP-1 lactylation in macrophages in acute lung injury. [PDF]

Front Immunol
Wang D, Gong Y, Chen Y, Wang Z, Yin J, Wang Z, Yang X, Zhang Y, Huang J, Jiang Z.   +9 more
europepmc   +1 more source

Enterococcus faecalis Translocation in Sepsis: Fibrinolysis and Mitochondrial Dysfunction Drive Lung Injury. [PDF]

J Cell Mol Med
Wang C, Lv D, Gao Y, Xu X, Zhu C, Zhang S, Zhang K.   +6 more
europepmc   +1 more source

Advances in natural product-based nanoparticles for the treatment of acute lung injury. [PDF]

Mater Today Bio
Zheng Y, Zhao Y, Zhang S, Wang M, Wang X, Chen XL.   +5 more
europepmc   +1 more source