Results 1 to 10 of about 351,237 (332)
Gene therapy for lung neoplasms. [PDF]
Clin Chest Med, 2011 The field of gene therapy is still in its infancy, but significant accomplishments have been achieved. The ability to transfer genes safely and successfully into animals and patients clearly has been established. It is highly likely that in the near future, gene therapy will be shown to have clear therapeutic efficacy in diseases such as the treatment ...
Vachani A +6 more
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Adjuvant therapy for lung neuroendocrine neoplasms
World Journal of Clinical Oncology, 2021 Pulmonary neuroendocrine neoplasms (NENs) represent a minority of lung cancers and vary from slower growing pulmonary carcinoid (PC) tumors to aggressive small cell lung cancer (SCLC). While SCLC can account for up to 15% of lung cancer, PCs are uncommon and represent about 2% of lung cancers.
Katharine E. Thomas +5 more
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The Surgical Management of Lung Neuroendocrine Neoplasms [PDF]
Cancers, 2023 This review summarizes key recent developments relevant to the surgical management of lung neuroendocrine neoplasms (L-NENs), including typical and atypical carcinoids, large cell neuroendocrine carcinoma, and small cell lung carcinoma. This review includes recent insights into the classification, clinical presentation, diagnostic workup, treatment ...
Patrick Soldath +1 more
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Neuroendocrine Neoplasms of the Lung
AJSP: Reviews and Reports, 2021 Abstract In this review, we discuss the clinical and pathologic aspects of epithelial neuroendocrine neoplasms of the lung and compare the current classification with that of gastrointestinal (GI) neuroendocrine neoplasms. Endocrine neoplasms can be broken down into 2 major categories, which, as currently believed, are not part
Kristin Stashek, Allen Burke
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Pathology & Oncology Research, 2020 With the discovery of rapamycin 45 years ago, studies in the mechanistic target of rapamycin (mTOR) field started 2 decades before the identification of the mTOR kinase. Over the years, studies revealed that the mTOR signaling is a master regulator of homeostasis and integrates a variety of environmental signals to regulate cell growth, proliferation ...
Anna Sebestyén +2 more
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A molecular map of lung neuroendocrine neoplasms [PDF]
GigaScience, 2020 Abstract Background Lung neuroendocrine neoplasms (LNENs) are rare solid cancers, with most genomic studies including a limited number of samples. Recently, generating the first multi-omic dataset for atypical pulmonary carcinoids and the first methylation dataset for large-cell neuroendocrine ...
Aurélie A G Gabriel +9 more
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Neuroendocrine neoplasms of the lung: a pathology update [PDF]
memo - Magazine of European Medical Oncology, 2021 Summary Purpose Neuroendocrine tumors and neuroendocrine carcinomas in the lung are distinct and separate entities featuring neuroendocrine differentiation, for which an accurate classification is clinically warranted. Materials and methods Three perspectives were addressed:
Metovic J., Barella M., Pelosi G.
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Lymphoproliferative Neoplasms of the Lung: A Review
Archives of Pathology & Laboratory Medicine, 2013 Context.—Diagnosis and classification of lymphomas are based on the morphologic, immunologic, and genetic features that the lesional cells share with their normal B and T lymphocyte counterparts. Primary pulmonary lymphomas account for 0.3% of primary lung neoplasms and less than 0.5% of all lymphomas.Objective.—To describe and summarize the clinical ...
Josette William +3 more
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Neoplasms of the Lungs and Bronchi
British Journal of Radiology: BIR Section, 1925 Malignant disease of the lungs is considered to be such a rarity, that it is usually given no more than a paragraph in our text books and is consequently seldom brought up in discussion of differential diagnosis. As long ago as 1889, Hare estimated that of all the deaths from pulmonary disease in London, 2·3 per cent, were due to primary neoplasms.
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Updates on lung neuroendocrine neoplasm classification
Histopathology, 2023 Lung neuroendocrine neoplasms (NENs) are a heterogeneous group of pulmonary neoplasms showing different morphological patterns and clinical and biological characteristics. The World Health Organisation (WHO) classification of lung NENs has been recently updated as part of the broader attempt to uniform the classification of NENs.
Vocino Trucco, Giulia +3 more
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