Primary lung neoplasms presenting as multiple synchronous lung nodules [PDF]
European Respiratory Review, 2020 Multiple synchronous lung nodules are frequently encountered on computed tomography (CT) scanning of the chest and are most commonly either non-neoplastic or metastases from a known primary malignancy.
Subha Ghosh +4 more
doaj +5 more sources
Machine Learning System for Lung Neoplasms Distinguished Based on Scleral Data [PDF]
Diagnostics, 2023 Lung cancer remains the most commonly diagnosed cancer and the leading cause of death from cancer. Recent research shows that the human eye can provide useful information about one’s health status, but few studies have revealed that the eye’s features ...
Qin Huang +11 more
doaj +3 more sources
Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA. [PDF]
Nat Commun, 2015 Lungs resected for adenocarcinomas often harbour minute discrete foci of cytologically atypical pneumocyte proliferations designated as atypical adenomatous hyperplasia (AAH).
Izumchenko E +12 more
europepmc +3 more sources
Dual targeting PET tracer [68Ga]Ga-FAPI-RGD in patients with lung neoplasms: a pilot exploratory study. [PDF]
Theranostics, 2023 Rationale: Early discovery, accurate diagnosis, and staging of lung cancer is essential for patients to receive appropriate treatment. PET/CT has become increasingly recognized as a valuable imaging modality for these patients, but there remains room for
Wang R +10 more
europepmc +2 more sources
The Surgical Management of Lung Neuroendocrine Neoplasms [PDF]
Cancers, 2023 Simple Summary Lung neuroendocrine neoplasms comprise a diverse group of cancers that arise from pulmonary neuroendocrine cells. They account for about 20% of all primary lung cancers and classify into four subtypes: typical carcinoid, atypical carcinoid,
Patrick Soldath +1 more
openalex +2 more sources
Epigenome-wide association study of smoking and DNA methylation in non-small cell lung neoplasms. [PDF]
Oncotarget, 2016 Tobacco smoke is a well-established lung cancer carcinogen. We hypothesize that epigenetic processes underlie carcinogenesis. The objective of this study is to examine the effects of smoke exposure on DNA methylation to search for novel susceptibility ...
Freeman JR, Chu S, Hsu T, Huang YT.
europepmc +2 more sources
Journal of Orthopaedic Surgery and Research, 2020 Background Large population-based studies of risk factor for lung metastases at the presentation with primary osseous neoplasms are lacking and necessary.
Lin Xie +4 more
doaj +2 more sources
Research Progress of Klotho in Lung Neoplasms [PDF]
Chinese Journal of Lung Cancer, 2023 Klotho gene was originally discovered as an anti-aging gene, Klotho protein encoded by Klotho gene is expressed in multiple human tissues, and its most prominent function is the regulation of phosphate homeostasis.
Jing WANG +6 more
doaj +2 more sources
Pathology & Oncology Research, 2020 With the discovery of rapamycin 45 years ago, studies in the mechanistic target of rapamycin (mTOR) field started 2 decades before the identification of the mTOR kinase. Over the years, studies revealed that the mTOR signaling is a master regulator of homeostasis and integrates a variety of environmental signals to regulate cell growth, proliferation ...
Ildiko, Krencz +2 more
openaire +3 more sources
Novel immunohistochemical assay utilizing the INSM1 (SP493) antibody demonstrates high specificity and sensitivity in detecting primary neuroendocrine lung neoplasms [PDF]
Diagnostic PathologyIntroduction About 15–20% of lung neoplasms are of neuroendocrine origin. In addition to evaluation of morphological features, these neoplasms can be identified by immunohistochemistry (IHC) using antibodies against neuroendocrine markers such as ...
Katerina Dvorak +2 more
doaj +2 more sources