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Primary lung neoplasms presenting as multiple synchronous lung nodules [PDF]
European Respiratory Review, 2020 Multiple synchronous lung nodules are frequently encountered on computed tomography (CT) scanning of the chest and are most commonly either non-neoplastic or metastases from a known primary malignancy.
Subha Ghosh +4 more
doaj +3 more sources
Dual targeting PET tracer [68Ga]Ga-FAPI-RGD in patients with lung neoplasms: a pilot exploratory study. [PDF]
Theranostics, 2023 Rationale: Early discovery, accurate diagnosis, and staging of lung cancer is essential for patients to receive appropriate treatment. PET/CT has become increasingly recognized as a valuable imaging modality for these patients, but there remains room for
Wang R +10 more
europepmc +2 more sources
Machine Learning System for Lung Neoplasms Distinguished Based on Scleral Data [PDF]
Diagnostics, 2023 Lung cancer remains the most commonly diagnosed cancer and the leading cause of death from cancer. Recent research shows that the human eye can provide useful information about one’s health status, but few studies have revealed that the eye’s features ...
Qin Huang +11 more
doaj +2 more sources
The Surgical Management of Lung Neuroendocrine Neoplasms [PDF]
Cancers, 2023 Simple Summary Lung neuroendocrine neoplasms comprise a diverse group of cancers that arise from pulmonary neuroendocrine cells. They account for about 20% of all primary lung cancers and classify into four subtypes: typical carcinoid, atypical carcinoid,
Patrick Soldath, R. Petersen
semanticscholar +4 more sources
Epigenome-wide association study of smoking and DNA methylation in non-small cell lung neoplasms. [PDF]
Oncotarget, 2016 Tobacco smoke is a well-established lung cancer carcinogen. We hypothesize that epigenetic processes underlie carcinogenesis. The objective of this study is to examine the effects of smoke exposure on DNA methylation to search for novel susceptibility ...
Freeman JR, Chu S, Hsu T, Huang YT.
europepmc +2 more sources
Journal of Orthopaedic Surgery and Research, 2020 Background Large population-based studies of risk factor for lung metastases at the presentation with primary osseous neoplasms are lacking and necessary.
Lin Xie +4 more
doaj +2 more sources
Research Progress of Klotho in Lung Neoplasms [PDF]
Chinese Journal of Lung Cancer, 2023 Klotho gene was originally discovered as an anti-aging gene, Klotho protein encoded by Klotho gene is expressed in multiple human tissues, and its most prominent function is the regulation of phosphate homeostasis.
Jing WANG +6 more
doaj +2 more sources
Pathology & Oncology Research, 2020 With the discovery of rapamycin 45 years ago, studies in the mechanistic target of rapamycin (mTOR) field started 2 decades before the identification of the mTOR kinase. Over the years, studies revealed that the mTOR signaling is a master regulator of homeostasis and integrates a variety of environmental signals to regulate cell growth, proliferation ...
I. Krencz, A. Sebestyén, A. Khoor
semanticscholar +4 more sources
Gene therapy for lung neoplasms. [PDF]
Clin Chest Med, 2011 The field of gene therapy is still in its infancy, but significant accomplishments have been achieved. The ability to transfer genes safely and successfully into animals and patients clearly has been established. It is highly likely that in the near future, gene therapy will be shown to have clear therapeutic efficacy in diseases such as the treatment ...
Vachani A +6 more
europepmc +6 more sources
A molecular map of lung neuroendocrine neoplasms [PDF]
GigaScience, 2020 Background Lung neuroendocrine neoplasms (LNENs) are rare solid cancers, with most genomic studies including a limited number of samples. Recently, generating the first multi-omic dataset for atypical pulmonary carcinoids and the first methylation ...
Aurélie A G Gabriel +9 more
semanticscholar +4 more sources