Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Diffuse cryptococcosis simulating lung and skin neoplasms [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2023 Raphael de Oliveira e Silva +1 more
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Importance of cancer among the Brazilian elderly population from 2000 to 2005 [PDF]
Einstein (São Paulo), 2009 Objective: To describe cancer hospital morbidity and mortality in the Brazilian elderly population according to the primary site of neoplasms per Brazilian region and their importance on Public Health System expenses. Methods: The data were obtained from
Angelo Bezerra de Souza Fêde +8 more
doaj
Prevalence of Delta-Like Protein 3 in a Consecutive Series of Surgically Resected Lung Neuroendocrine Neoplasms [PDF]
, 2021 Greta Alì +8 more
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Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Risk of subsequent primary neoplasms developing in lung cancer patients with prior malignancies [PDF]
, 2004 Malcolm V. Brock +6 more
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Neoplasm of Lung. (? Teratoma) [PDF]
Proceedings of the Royal Society of Medicine, 1934 R. W. B. Ellis, H. Thursfield
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Molecular Oncology, EarlyView.This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
Diagnostic Value of Conventional PET Parameters and Radiomic Features Extracted from 18F-FDG-PET/CT for Histologic Subtype Classification and Characterization of Lung Neuroendocrine Neoplasms [PDF]
, 2021 Philippe Thuillier +10 more
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YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source