Results 141 to 150 of about 342,678 (334)

Cystic Lung Phantom to Validate Clinical CT Protocols [PDF]

open access: yesarXiv
In CT-based evaluation of the extent of cystic changes in the lungs of patients with cystic lung diseases, such as Lymphangioleiomyomatosis (LAM), there is a lack of a lung phantom containing air-filled cavities that mimic pulmonary cysts to calibrate the measurement of cystic volumes from CT scans.
arxiv  

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

Primary pulmonary undifferentiated pleomorphic sarcoma (PPUPS)

open access: yesAutopsy and Case Reports, 2019
Undifferentiated pleomorphic sarcoma (UPS) is a high-grade pleomorphic neoplasm with no identifiable line(s) of differentiation using currently available diagnostic techniques.
Amir Qorbani, Scott D Nelson
doaj  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Validation of High-Resolution Multimodality Imaging of Pretreatment Lung Function in Pulmonary Neoplasms [PDF]

open access: bronze, 2012
Tejan Diwanji   +4 more
openalex   +1 more source

POS1189-HPR LUNG AND MYELOPROLIFERATIVE NEOPLASMS IN RHEUMATOID ARTHRITIS PATIENTS TREATED WITH JANUS KINASE INHIBITORS: A REVIEW OF THE LITERATURE [PDF]

open access: bronze, 2023
O. Hamdi   +10 more
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

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