Results 51 to 60 of about 351,237 (332)

Higher order organizational features can distinguish protein interaction networks of disease classes: a case study of neoplasms and neurological diseases [PDF]

arXiv, 2022
Neoplasms (NPs) and neurological diseases and disorders (NDDs) are amongst the major classes of diseases underlying deaths of a disproportionate number of people worldwide. To determine if there exist some distinctive features in the local wiring patterns of protein interactions emerging at the onset of a disease belonging to either of these two ...
arxiv  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Patient with recurrent paratesticular malignant mesothelioma and multiple primary neoplasms [PDF]

Journal of Men's Health
Paratesticular malignant mesothelioma (MM) is a rare tumor frequently associated with asbestos exposure. Therefore, we present an even rarer case of a 78-year-old male patient diagnosed with multiple primary neoplasms, including prostate cancer, lung ...
Kyung Hwan Kim, Yury Lee, Ja Yoon Ku, Hong Koo Ha, Hyun Jun Park   +4 more
doaj   +1 more source

A Hierarchical Transformer Encoder to Improve Entire Neoplasm Segmentation on Whole Slide Image of Hepatocellular Carcinoma [PDF]

arXiv, 2023
In digital histopathology, entire neoplasm segmentation on Whole Slide Image (WSI) of Hepatocellular Carcinoma (HCC) plays an important role, especially as a preprocessing filter to automatically exclude healthy tissue, in histological molecular correlations mining and other downstream histopathological tasks.
arxiv  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Results of surgical treatment of patients with lung cancer

Archivo Médico de Camagüey, 2021
Background: the incidence of lung cancer in the province of Sancti Spíritus is high and its diagnosis is usually made in advanced stages, for which surgical treatment is not always possible.
Orlando Silvio Rodríguez-Martínez, Miguel Emilio García-Rodríguez, Miguel Alexánder Concepción-López, Jorge Héctor Rojas-Sánchez, Sandra Moreno-Perera   +4 more
doaj  

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Inflammatory myofibroblastic tumor of the lung in pregnancy mimicking carcinoid tumor

Lung India, 2016
Inflammatory myofibroblastic tumors (IMT) are uncommon neoplasms of the lung in adults. They constitute less than 1% of all lung neoplasms and usually present as parenchymal masses. Diagnosis requires a high index of suspicion.
Venkata Nagarjuna Maturu, Amanjit Bal, Navneet Singh   +2 more
doaj   +1 more source

Lung segmentation on chest x-ray images in patients with severe abnormal findings using deep learning [PDF]

, 2019
Rationale and objectives: Several studies have evaluated the usefulness of deep learning for lung segmentation using chest x-ray (CXR) images with small- or medium-sized abnormal findings. Here, we built a database including both CXR images with severe abnormalities and experts' lung segmentation results, and aimed to evaluate our network's efficacy in
arxiv   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source