Results 181 to 190 of about 1,217,238 (259)

Clinical and Genetic Analysis of Pediatric Neurodevelopmental Disorders With Complex Chromosomal Rearrangements in Two Cases

Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
This study investigates the impact of complex chromosomal rearrangement (CCR) breakpoints on pediatric developmental delay and epilepsy. By integrating karyotype analysis with WES and/or WGS, we identified an inversion on chromosome 3 likely affecting ROBO1/DNAJC13/ACAD11 in one patient and a complex chromosome 1 rearrangement with a novel KCNA2 ...
Jiaci Li, Wenxuan Fan, Nan Liu, Shuyue Zhang, Ping Wang, Chunyu Gu, Jianbo Shu   +6 more
wiley   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

TLR7 Agonist Nanomedicine Suppresses Lung Metastasis of Osteosarcoma by Remodeling the Immune Microenvironment

MedComm – Oncology, Volume 5, Issue 3, September 2026.
In tail‐vein and orthotopic osteosarcoma mouse models, 1V209‑Cho‑Lip, a TLR7 agonist liposome, effectively suppresses pulmonary metastasis and prolongs survival. Flow cytometry and single‑cell transcriptomics reveal that 1V209‑Cho‑Lip remodels both the pre‑metastatic and post‑metastatic immune microenvironments, alleviates myeloid‑mediated ...
Xinyue Zhang, Hao Zeng, Furong Qin, Yuquan Wei, Dandan Wan, Xiawei Wei   +5 more
wiley   +1 more source

Ventilation Imaging of the Lung at 0.55T With Continuous Slice Cycling

Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1235-1244, September 2026.
ABSTRACT Purpose To propose and evaluate a novel method for pulmonary ventilation imaging, offering considerably improved SNR. Methods A continuous slice cycling (CSC) acquisition scheme is proposed to exclusively capture signal modulations from respiratory motion with increased SNR.
Andrea Leuthard, Grzegorz Bauman, Katrin E. Hostettler, Maurice Pradella, Oliver Bieri   +4 more
wiley   +1 more source

Isolated Central Nervous System Tuberculosis‐Associated Immune Reconstitution Inflammatory Syndrome—Case Report and Literature Review

Respirology Case Reports, Volume 14, Issue 9, September 2026.
Disseminated tuberculosis in an immunocompetent young male initially improved with anti‐tuberculosis therapy. Early treatment was complicated by drug‐induced liver injury and paradoxical isolated CNS‐TB‐IRIS with new intracranial lesions despite systemic disease regression.
Mithen Ravisankar, Muniza Bai, Vignesh Kumar Kathiresan, Jefferson Daniel Jawahar, Balamugesh Thangakunam, Angel Miraclin Thirugnanakumar, Elanthenral Sigamani   +6 more
wiley   +1 more source

Quantitative And Qualitative Analysis For Lung Nodule Segmentation

International Journal of Electronics and Communication Engineering, 2019
Rabiya Banu A, Kannan R
openaire   +1 more source

Transbronchial Access of Solitary Pulmonary Nodules Without Bronchus Sign Using a Novel Puncture Dilatation Catheter: Initial Feasibility Experience

Respirology Case Reports, Volume 14, Issue 9, September 2026.
This case series reports the initial clinical experience using a novel, single‐use transbronchial puncture dilatation catheter compatible with thin bronchoscopes. In two distinct cases involving a lung nodule with negative bronchus sign and a stenotic airway, the device successfully facilitated ‘off‐road’ access and radial EBUS verification, enabling ...
Sze Shyang Kho, Chan Sin Chai
wiley   +1 more source

Rescue Diagnosis of Upper‐Lobar Station 12U Lymph Nodes Using the Thin Convex‐Probe EBUS Bronchoscope (BF‐UCP190F): A Report of Two Cases

Respirology Case Reports, Volume 14, Issue 9, September 2026.
When conventional bronchoscopic forceps biopsy is non‐diagnostic, the TCP‐EBUS bronchoscope (BF‐UCP190F) enables real‐time EBUS‐TBNA of upper‐lobar station 12 lymph node via B3. This rescue approach establishes the definitive pathological diagnosis and directly guides subsequent treatment, highlighting the potential of TCP‐EBUS to expand the diagnostic
Toki Kitano, Yuki Takigawa, Ken Sato, Mayu Goda, Hitoshi Hara, Tomoya Osedo, Yuto Sasano, Keisuke Shiraha, Suzuka Matsuoka, Jun Nishimura, Hiromi Watanabe, Kenichiro Kudo, Keiichi Fujiwara   +12 more
wiley   +1 more source

Lung cancer detection in CT scans using extracted nodule features and precise multistage segmentation with deep learning based ensemble model. [PDF]

Sci Rep
B S, S P V, Babu SY, Mishra S, Ezhilmaran D.   +4 more
europepmc   +1 more source

Pulmonary AL Amyloidosis as a Cause of Interstitial Lung Disease Diagnosed With Transbronchial Lung Biopsy

Respirology Case Reports, Volume 14, Issue 9, September 2026.
Importance of tissue diagnosis in pulmonary amyloidosis, a rare albeit treatable cause of interstitial lung disease. ABSTRACT Pulmonary amyloidosis is a rare manifestation of amyloid deposition which can present as a rare albeit treatable cause of interstitial lung disease.
Kai Wen Hwang, Ju Ee Seet, Michelle Poon, Kay Choong See   +3 more
wiley   +1 more source