Results 211 to 220 of about 219,832 (311)

Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

Advanced Science, EarlyView.
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao, Chengming Qu, Yanzhao Zhou, Xiaoqian Wang, Xiangjun Qian, Xun Chen, Feng Han, Xiaokai Zhang, Yiyi Ji, Han Li, ChengWei Ju, Peng Xia, Weiwei Tang, Hao Zhuang, Jinxue Zhou   +14 more
wiley   +1 more source

Sternal Complications After Clamshell Surgery for (Heart-)Lung Transplantation-A Systematic Literature Review. [PDF]

Eur J Cardiothorac Surg
Klei DS, Sabaoğlu R, Mokhles MM, de Heer LM, van Wessem KJP.   +4 more
europepmc   +1 more source

Cell Origin of Donor-Derived cfDNA in the Early Post-Transplant Period is Primarily Leukocyte Origin, Not Donor Lung Origin [PDF]

H. Yamamoto, A. Sundby, Jared Allen, Shaf Keshavjee, Gavin W. Wilson, Jonathan Yeung   +5 more
openalex   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Cytomegalovirus and Crohn's disease as competing causes of small bowel inflammation after double-lung transplantation. [PDF]

Eur Clin Respir J
Niklassen JH, Hvas CL, Schønning K, Moestrup KS, Helleberg M, Perch M, Bendstrup E.   +6 more
europepmc   +1 more source

Microbiome and metabolome patterns after lung transplantation reflect underlying disease and chronic lung allograft dysfunction [PDF]

Christian Martin, Kathleen Mahan, Talia D. Wiggen, Adam Gilbertsen, Marshall I. Hertz, Ryan C. Hunter, Robert A. Quinn   +6 more
openalex   +1 more source

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

Lung Transplantation Following Paraquat Poisoning: Time to Think. [PDF]

Respirol Case Rep
Gonuguntla HK, Tripathi S, Varghese V, Goda S, Vaddepally CR, Kavumkal Rajagopalan B, Kumar MS, Vidyasagar BP.   +7 more
europepmc   +1 more source

Current Status of Multidisciplinary Treatment Strategies for Hepatocellular Carcinoma in the Era of Advanced Systemic Therapies

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT The therapeutic landscape of hepatocellular carcinoma (HCC) has been transformed by recent advancements in systemic therapies, particularly with the introduction of immune checkpoint inhibitors, expanding treatment options beyond conventional locoregional approaches.
Keiichi Akahoshi, Shun Kaneko, Shinji Tanaka, Minoru Tanabe, Daisuke Ban   +4 more
wiley   +1 more source

Native lung aspergilloma after single lung transplantation-a case series. [PDF]

J Thorac Dis
Tsviban L, Kramer MR, Fridel L, Shostak Y, Shitenberg D, Rosengarten D, Heching M, Pesachovich Y, Barac YD, Shtraichman O.   +9 more
europepmc   +1 more source