Results 261 to 270 of about 3,067,002 (353)

A European multicentre, randomised controlled trial of pirfenidone in bronchiolitis obliterans syndrome after bilateral lung transplantation. [PDF]

Eur Respir J
Perch M, Corris P, Lordan J, Bessa V, Magnusson J, Verleden GM, Vos R, Kneidinger N, Leuckfeld I, Verschuuren E, Gottlieb J.   +10 more
europepmc   +1 more source

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

Clinical Pharmacology &Therapeutics, EarlyView.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra, Viktoriia Starokozhko, Elisabeth Bakker, Anna Maria Gerdina Pasmooij, Peter Gerardus Maria Mol   +4 more
wiley   +1 more source

Redo Lung Transplantation After Heart-lung Transplantation. [PDF]

Ann Thorac Surg Short Rep
Chan JCY, Geraci TC, Angel LF, Chang SH.
europepmc   +1 more source

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

Anti-HLA antibodies in lung transplantation: diagnostic pitfalls and future directions. [PDF]

Eur Respir Rev
Zajacova A, Revilla-Lopez E, Guney M, De Pelsmaeker S, Emonds MP, Naesens M, Saez-Gimenez B, Vanaudenaerde BM, Vos R.   +8 more
europepmc   +1 more source

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Seeing is believing: Mouse orthotopic vascularized right lung transplantation

JHLT Open
Jin Zhao, Xiucheng Yang, Bingqing Yue, Jingyu Chen   +3 more
doaj   +1 more source

Case report: Double-lung transplantation for Hermansky-Pudlak syndrome-associated pulmonary fibrosis and early-stage lung cancer. [PDF]

Front Immunol
Li X, Ding L, Li B, Ding Z, Wang K, Li J, Gao X.   +6 more
europepmc   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

Intraoperative Extracorporeal Life Support for Bilateral Sequential Lung Transplantation. [PDF]

J Clin Med
Kopjar T, Dzubur F, Hirsl D, Glodic G, Madzarac G, Planinc M, Spicek Macan J, Colak Z, Gasparovic H, Samarzija M.   +9 more
europepmc   +1 more source