Results 131 to 140 of about 1,366,002 (305)

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

open access: yesAdvanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao   +7 more
wiley   +1 more source

Hemorrhage Detection during Focused-Ultrasound Induced Blood-Brain- Barrier Opening by Using Susceptibility-Weighted Magnetic Resonance Imaging

open access: yes, 2009
High-intensity focused ultrasound has been discovered to be able to locally and reversibly increase the permeability of the blood–brain barrier (BBB), which can be detected using magnetic resonance imaging (MRI ).
LIU, HAO-LI;WAI, YAU-YAU;CHEN, WEN- SHIANG;CHEN, JIN-CHUNG;WU, XIN-YU;HUANG, WEN-CHENG;YEN, TZU-CHEN;WANG, JIUN-JIE   +1 more
core   +1 more source

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

open access: yesAdvanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li   +9 more
wiley   +1 more source

Lung ultrasound: Present and future

open access: yesLung India, 2015
The scope of lung ultrasound (LUS) in emergency and critical care settings has been studied extensively. LUS is easily available at bedside, free of radiation hazard and real time. All these features make it useful in reducing need of bedside X-rays and CT scan of chest.
openaire   +3 more sources

Lung Ultrasound Assessment of Lung Hyperinflation in Patients with Stable COPD: An Effective Diagnostic Tool

open access: yes
Yongjian Chen,1 Jingyun Li,2 Zhixing Zhu,3 Guorong Lyu1,2 1Department of Ultrasound, the Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, People’s Republic of China; 2School of Medicine, Quanzhou Medical College, Quanzhou ...
Li J, Zhu Z, Lyu G, Chen Y
core  

Volumetric Assessment of Normal Fetal Lungs Using Three-Dimensional Ultrasound

open access: yes, 2009
We attempted to construct normal reference centiles of fetal lung volume (LV) for clinical application by using three- dimensional (3-D) ultrasound (US) during normal gestation.
張炯心;游振祥;張峰銘;柯慧貞;陳皙堯   +1 more
core  

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

open access: yesAdvanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu   +10 more
wiley   +1 more source

New lung ultrasound system for rapid triage of pulmonary disease without a radiologist or sonographer

open access: yesBMC Pulmonary Medicine
Background Most people in the world lack access to medical imaging including for assessment of pulmonary disease. We sought to improve access to pulmonary imaging by developing a rapid automated system for triage of pulmonary disease using lung ...
Thomas J. Marini   +13 more
doaj   +1 more source

A Pancreatitis‐Inspired Trypsinogen Nanoplatform Reprograms Tumor‐Associated Macrophages via NF‐κB for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Trypsinogen‐loaded nanoparticles reprogram TAMs via NF‐κB/NLRP3, driving M2→M1 conversion and potent phagocytosis to unleash antitumor immunity. ABSTRACT Although reprogramming tumor‐associated macrophages (TAMs) represents a promising therapeutic strategy, approaches that are both precise and safe remain scarce.
Lei Cao   +7 more
wiley   +1 more source

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