Results 111 to 120 of about 11,593,090 (249)

Evaluation of Quantitative Computed Tomography Indices in Patients with Pneumonia and Acute Respiratory Failure in the Intensive Care Unit (ICU)

Diagnostics
Background: In this study, we aimed to explore the relationship between quantitative indices derived from computed tomography (CT) attenuation histograms and disease prognosis in patients with pneumonia and acute respiratory failure.
Volkan Alparslan, Özgür Çakır, Özlem Güler, Yusuf Altıntaş, Pınar Kartal Köse, Sibel Balci, Ahmet Yalnız, Nur Baykara, Alparslan Kuş   +8 more
doaj   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Effects of obesity on lung volume and capacity in children and adolescents: a systematic review

Revista Paulista de Pediatria
Objective: To assess the effects of obesity on lung volume and capacity in children and adolescents. Data source: This is a systematic review, carried out in Pubmed, Lilacs, Scielo and PEDro databases, using the following Keywords: Plethysmography ...
Aline Dill Winck, João Paulo Heinzmann-Filho, Rafaela Borges Soares, Juliana Severo da Silva, Cristhiele Taís Woszezenki, Letiane Bueno Zanatta   +5 more
doaj   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

Review of lung sealant technologies for lung volume reduction in pulmonary disease

, 2018
Branislava Milenkovic,1,2 Sanja Dimic Janjic,2 Spasoje Popevic1,2 1Faculty of Medicine, University of Belgrade, Belgrade, Serbia; 2Clinic for Pulmonary Diseases, Clinical Center of Serbia, Belgrade, Serbia Abstract: Emphysema is an incurable and ...
Dimic Janjic S, Popevic S, Milenkovic B
core  

Characterizing extravascular lung water—A dual-contrast agent extracellular volume approach by cardiovascular magnetic resonance

Journal of Cardiovascular Magnetic Resonance
: Background: Pathological extravascular lung water is a facet of decompensated congestive heart failure that current cardiovascular magnetic resonance (CMR) methods fail to quantify.
Felicia Seemann, Rim N. Halaby, Andrea Jaimes, Kendall O’Brien, Peter Kellman, Daniel A. Herzka, Robert J. Lederman, Adrienne E. Campbell-Washburn   +7 more
doaj   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Optimisation and validation of virtual physiological human lung models in asthma

Physiological tests assessing abnormal lung function due to ventilation (V) and perfusion (Q) mismatch, and ventilation heterogeneity (VH)–such as the CO gas transfer and forced oscillation techniques (FOT)–provide valuable but global measurements of ...
Nikolaou, Christos
core   +1 more source

Subclinical impairment of the left atrium is associated with MRI-based lung volume but not with parameters from pulmonary function testing

Scientific Reports
Left atrial (LA) physiology and hemodynamics are intimately connected to cardiac and lung function in health and disease. This study examined the relationship between MRI-based left atrial (LA) size and function with MRI-based lung volume and pulmonary ...
Charlotte Wintergerst, Roberto Lorbeer, Blerim Mujaj, Bernard E. Bulwer, Susanne Rospleszcz, Esther Askani, Holger Schulz, Stefan Karrasch, Annette Peters, Christopher L. Schlett, Fabian Bamberg, Ricarda von Krüchten   +11 more
doaj   +1 more source