Results 231 to 240 of about 447,886 (300)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Effect of Trunk Rotation and Sex Differences on Lung Volume and Respiratory Muscle Strength in Healthy Young People. [PDF]

Cureus
Takahata M, Osawa M, Hoshina M, Yamaki M, Sato T.   +4 more
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Breath-by-breath quantification of inhaled nitric oxide absorption and modeling of methemoglobin kinetics. [PDF]

Redox Biol
Dong R, Wanderley HV, Mereto E, Safaee Fakhr B, Nardini R, Yu B, Berra L.   +6 more
europepmc   +1 more source

Salbutamol Reversal of Methacholine Induced Bronchoconstriction: Vibrating Mesh Nebulizer versus Pressurized Metered Dose Inhaler. [PDF]

J Asthma Allergy
Davis BE, Philipenko BS, Cockcroft DW.
europepmc   +1 more source

Defining thoracic impedance thresholds for rescue ventilation: a laboratory study. [PDF]

Resusc Plus
Jarrett P, Prakash R, Thakur B, Thomas J, Cao D, Chang M, Yang B, Shaver S, Idris A.   +8 more
europepmc   +1 more source

High-frequency oscillation improves mucus clearance and airway resistance in mechanically ventilated patients: a randomized clinical trial. [PDF]

Ann Intensive Care
Wang Y, Chen D, Xie W, Zhang R, Guo X, Wu H, Liu L, Yuan X.   +7 more
europepmc   +1 more source

Physical Therapy with Transfer of Energy Capacitive and Resistive (TECAR) radiofrequency therapy for multimodal care of Hypersensitivity Pneumonitis: A case report. [PDF]

Respir Med Case Rep
Giacomo J.
europepmc   +1 more source

Comparative assessment of extravascular lung water index in ARDS patients on veno-venous ECMO: transpulmonary thermodilution versus AI-driven chest CT segmentation. [PDF]

BMC Pulm Med
Otto M, Mohr D, Zimmermann J, Rathmann N, Boesing C, Thiel M, Krebs J, Luecke T, Rocco PRM, Conrad AM.   +9 more
europepmc   +1 more source