Results 111 to 120 of about 149 (146)

Carbon‐Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang   +10 more
wiley   +1 more source

RBC Membrane‐Camouflaged Nanosystem‐Mediated Synergistic Drug Combination for Enhanced Anti‐Tumor Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng   +6 more
wiley   +1 more source

CLDN18.2 CAR‐derived Extracellular Vesicle Immunotherapy Improves Outcome in Murine Pancreatic Cancer

open access: yesAdvanced Healthcare Materials, EarlyView.
CLDN18.2 CAR‐T cell‐derived small extracellular vesicles (CAR‐sEVs) display potent cytotoxicity and prolong survival in preclinical pancreatic cancer models. They contain functional CAR proteins and granzyme B, exhibit antigen specificity, and effectively target tumor cells while sparing healthy cells.
Yue Qing   +7 more
wiley   +1 more source

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

open access: yesAdvanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim   +11 more
wiley   +1 more source
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Lung volumes of singers

Journal of Applied Physiology, 1960
Lung volume determinations (tidal volume, inspiratory capacity, inspiratory reserve volume, expiratory reserve volume, vital capacity, maximum breathing capacity, functional residual capacity, residual volume, and total lung capacity) were carried out on 16 professional singers and 21 subjects who had had no professional vocal training. No differences
Stanley S. Heller   +2 more
openaire   +2 more sources

Measurement of Lung Volumes

Clinical Reviews in Allergy & Immunology, 2009
Lung volume measurements always determine total lung capacity (TLC), and most measurement techniques also determine functional residual capacity (FRC) and residual volume (RV). These measurements are needed less often than spirometry-derived values and require somewhat more difficult methods than required by spirometry.
Richard E. Kanner, Theodore G. Liou
openaire   +3 more sources

Effects of lung volume, volume history, and methacholine on lung tissue viscance

Journal of Applied Physiology, 1989
We examined the effects of lung volume change and volume history on lung resistance (RL) and its components before and during induced constriction. Eleven subjects, including three current and four former asthmatics, were studied. RL, airway resistance (Raw), and, by subtraction, tissue viscance (Vtis) were measured at different lung volumes before ...
E. P. Ingenito   +3 more
openaire   +3 more sources

LUNG VOLUMES AND ELASTICITY

Clinics in Chest Medicine, 2001
The respiratory system is an elastic structure changing volume when pressures are generated by inspiratory or expiratory muscles. If the muscles are relaxed the respiratory system returns to its relaxation volume (Vr) (referred to in the pediatric literature as the elastic equilibrium volume [EEV]), which in normal subjects is the end-expired volume or
openaire   +3 more sources

Bronchoscopic lung volume reduction

Multimedia Manual of Cardio-Thoracic Surgery, 2007
Emphysema is a debilitating lung disease continuing to be a major source of morbidity and mortality in the developed countries. Medical treatment is the mainstay of therapy and consists of smoking cessation, pulmonary rehabilitation, administration of bronchodilators and, when indicated, steroids and supplemental oxygen.
VENUTA, Federico   +3 more
openaire   +3 more sources

Lung volume, closing volume, and gas exchange

Journal of Applied Physiology, 1982
The effect of a voluntary reduction in lung volume on arterial O2 saturation (SaO2) was studied in 10 normal subjects aged 19–63 yr. SaO2 was measured by ear oximetry first during tidal breathing at functional residual capacity, and then during tidal breathing at 380 ml above residual volume.
Morrison, SC   +3 more
openaire   +3 more sources

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