Health and Quality of Life Outcomes, 2019 Background/purpose The LFA REAL™ is a measurement system for evaluating lupus disease activity from both clinician and patient perspectives. Patients’ viewpoints are captured using a patient-reported outcome (PRO) questionnaire. A series of visual analog
Anca D. Askanase +6 more
doaj +1 more source
Autoimmune diseases and their manifestations on oral cavity: diagnosis and clinical management [PDF]
, 2018 Oral signs are frequently the first manifestation of autoimmune diseases. For this reason, dentists play an important role in the detection of emerging autoimmune pathologies.
Bossù, Maurizio +5 more
core +2 more sources
BRWD1 orchestrates epigenetic landscape of late B lymphopoiesis
Nature Communications, 2018 B-cell development is tightly regulated by transcription programs that are coordinated by transcription factors (TF) and locus accessibility. Here the authors show that, in mice and humans, the epigenetic reader BRWD1 inhibits and promotes the ...
Malay Mandal +9 more
doaj +1 more source
A discrete cluster of urinary biomarkers discriminates between active systemic lupus erythematosus patients with and without glomerulonephritis. [PDF]
, 2016 BackgroundManagement of lupus nephritis (LN) would be greatly aided by the discovery of biomarkers that accurately reflect changes in disease activity.
Avila-Casado, Carmen +10 more
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Immunoregulatory soluble CTLA-4 modifies effector T cell responses in systemic lupus erythematosus [PDF]
, 2016 Acknowledgments This work was supported by Arthritis Research UK (Grant no. 19282). We are grateful to Dr. Nick Fluck for his invaluable support in recruiting patients for the study, and Mrs.
Barker, Robert N. +6 more
core +3 more sources
Very low-mass members of the Lupus 3 cloud
, 2005 We report on a multi-band survey for very low-mass stars and brown dwarfs in the Lupus 3 cloud with the Wide Field Imager (WFI) at the ESO/MPG 2.2m telescope on La Silla Observatory (Chile).
Alcalá +52 more
core +1 more source
High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids. [PDF]
, 2011 BackgroundPatients with systemic lupus erythematosus (SLE) are at increased risk of atherosclerosis, even after accounting for traditional risk factors.
Charles-Schoeman, Christina +14 more
core +2 more sources
Influence of 1 Alpha, 25-Dihydroxyvitamin D3 on T helper 17 cells and related cytokines in systemic lupus erythematosus [PDF]
, 2015 Background: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Emerging data suggests that T helper 17 (Th17) cells play a pathogenic role in SLE and the increased number of these cells correlates with disease activity.
Abdollahi, N. +7 more
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