Results 31 to 40 of about 1,279,892 (312)

Severe thrombocytopenia in antiphospholipid syndrome: a retrospective study of 432 patients

RMD Open
Introduction Antiphospholipid syndrome (APS) is an autoimmune disease characterised by obstetric morbidity and recurrent venous and/or arterial thrombosis.
Zahir Amoura, Alexis Mathian, Miguel Hie, Raphael Lhote, Micheline Pha, Fleur Cohen-Aubart, Julien Haroche, Matthias Papo, Quentin Moyon, Dov Taieb, Carine Schmidt, Pierre-Louis Cariou, Nassim Ait Abdallah   +12 more
doaj   +1 more source

The significance of M1/M2 macrophage-like monocytes in children with systemic lupus erythematosus

European Journal of Inflammation, 2019
Monocytes/macrophages are important in the development of systemic lupus erythematosus. To research M1 and M2 macrophage-like monocytes in the peripheral blood of children with systemic lupus erythematosus and explore the clinical significance, M1 and M2
Xiao-Ling Niu, Dan Feng, Sheng Hao, Xin-Yu Kuang, Ying Wu, Guang-Hua Zhu, Wen-Yan Huang   +6 more
doaj   +1 more source

Serum interleukin-17 levels are associated with nephritis in childhood-onset systemic lupus erythematosus

Clinics, 2015
OBJECTIVES: To determine the serum interleukin-17 (IL-17) levels in childhood-onset systemic lupus erythematosus patients and to evaluate the association between IL-17 and clinical manifestations, disease activity, laboratory findings and treatment ...
Karina de Oliveira Peliçari, Mariana Postal, Nailú Angelica Sinicato, Fernando Augusto Peres, Paula Teixeira Fernandes, Roberto Marini, Lilian Tereza Lavras Costallat, Simone Appenzeller   +7 more
doaj   +1 more source

A Toll for lupus [PDF]

, 2005
Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
Anders, Hans-Joachim, H-J Anders
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Serum S100A12 levels in children with childhood-onset systemic lupus erythematosus, systemic juvenile arthritis, and systemic undefined recurrent fevers

Zeitschrift für Rheumatologie, 2021
We compared serum levels of S100A12, a proinflammatory protein predominantly secreted by neutrophils, in children with newly diagnosed childhood-onset systemic lupus erythematosus (cSLE), systemic juvenile arthritis (sJIA), and systemic undefined recurrent fevers (SURFS) to examine its role as a diagnostic and discriminative marker of inflammation and ...
Dubravka Bobek, Mario Sestan, Luciana Mijacika, Natasa Kovacic, Ivan Kresimir Lukic, Danka Grcevic, Marija Jelusic   +6 more
openaire   +4 more sources

Review of presentations at the 6th European Lupus Meeting 3-5 March 2005. [PDF]

, 2005
The 6th European Lupus Meeting was held at the Royal College of Physicians of London and was attended by 450 delegates. The conference brought together leading speakers from Europe and North America who reviewed current knowledge and exciting new ...
Rahman, A, Ioannou, Y, Giles, IP, Bowman, SJ   +3 more
core  

Differential impact of systemic lupus erythematosus and rheumatoid arthritis on health-related quality of life

, 2017
This study examined and compared health-related quality of life (QoL) in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA)
Alpizar-Rodriguez, D., Ribi, Camillo, Courvoisier, Delphine, Alpizar-Rodriguez, Deshire, Finckh, A., Finckh, Axel, Chaigne, B., Chaigne, Benjamin, Chizzolini, Carlo, Ribi, C., Chizzolini, C., Courvoisier, D., Chizzolini C, Delphine Courvoisier, Finckh A, Deshire Alpizar-Rodriguez, Chaigne B, Ribi C, Carlo Chizzolini, Axel Finckh, Alpizar-Rodriguez D, null null, Courvoisier D, Benjamin Chaigne, Camillo Ribi   +24 more
core   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Acute interstitial nephritis and drug-induced systemic lupus erythematosus due to chlorthalidone and amiodarone: A case report

SAGE Open Medical Case Reports, 2020
Drug-induced lupus erythematosus has features distinct from primary systemic lupus erythematosus. It can occur with a wide variety of agents that result in the generation of anti-histone or other types of antibodies.
Umut Selamet, Ramy M Hanna, Anthony Sisk, Lama Abdelnour, Lena Ghobry, Ira Kurtz   +5 more
doaj   +1 more source