Systemic lupus erythematosus clinically resembling multiple sclerosis and with unusual pathological and ultrastructural features. [PDF]
, 1979 Ingrid V. Allen +3 more
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Advanced Science, EarlyView.This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi +11 more
wiley +1 more source
Acute pancreatitis as an initial presentation of systemic lupus erythematosus: a case report
Journal of Medical Case ReportsBackground Systemic lupus erythematosus is a systemic autoimmune disease affecting different organ systems. Gastrointestinal symptoms in patients with systemic lupus erythematosus are common. But systemic lupus erythematosus-related acute pancreatitis is
Mengyu Li, Sutong Li
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OP0201 INCREASED RISK OF DEMENTIA IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS [PDF]
, 2020 J. Lee +9 more
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Advanced Science, EarlyView.Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu +7 more
wiley +1 more source
Medical geography and its contribution to the aetiology of rare systemic connective tissue diseases : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Geography at Massey University [PDF]
, 1975 This thesis is in two interrelated parts. Part One traced the historical development of medical geography since the idea of applying a geographical perspective to medical problems was first mooted in 4 B.C.
Borman, Graham Barry
core
Systemic Lupus Erythematosus and Irritable Bowel Syndrome: Is Blastocystis Hominis the Missing Piece of the Puzzle [PDF]
, 2018 Mohammed M. Keshawy, Maha Alabbassy
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Advanced Science, EarlyView.IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang +11 more
wiley +1 more source
Modulation of interferon-[alpha] secretion by activated platelets in systemic lupus erythematosus. [PDF]
, 2008 Type I interferons play a key role in systemic lupus erythematosus (SLE) pathogenesis as an "IFN signature" is found in the majority of patients with active SLE.
Bernard Weill +8 more
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AB0169 SNP (1513A>C AND 489C>T) OF P2X7 RECEPTOR IN SYSTEMIC LUPUS ERYTHEMATOSUS WITH SEROSITIS [PDF]
, 2019 Federica Furini +5 more
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