Results 301 to 310 of about 371,009 (363)

The 15‐Year Survival Advantage: Immune Resilience as a Salutogenic Force in Healthy Aging

Aging Cell, EarlyView.
Human aging shows puzzling diversity: similar aging rates yet vastly different health outcomes. Our study of ~17,500 people revealed a health‐promoting trait (more common in women) linked to strong immune resilience and high expression of TCF7, a key immune gene. This trait enables individuals to fight infections like COVID‐19 more effectively, respond
Muthu Saravanan Manoharan, Grace C. Lee, Nathan Harper, Justin A. Meunier, Marcos I. Restrepo, Fabio Jimenez, Sreenath Karekatt, Anne P. Branum, Alvaro A. Gaitan, Kian Andampour, Alisha M. Smith, Michael Mader, Michelle Noronha, Devjit Tripathy, Nu Zhang, Alvaro G. Moreira, Lavanya Pandranki, South Texas Veterans Health Care System (STVHCS) COVID‐19 Clinical team, STVHCS COVID‐19 Vaccine team, STVHCS COVID‐19 Convalescent care team, STVHCS Center for Personalized Medicine, Sandra Sanchez‐Reilly, Hanh D. Trinh, Clea Barnett, Luis Angel, Leopoldo N. Segal, Susannah Nicholson, Robert A. Clark, Weijing He, Jason F. Okulicz, Sunil K. Ahuja, Andrew Carrillo, Chanda Dhami, Gaeun Jo, Krupa Jiva, Ernesto Robinson, Caitlyn A. Winter, Lauryn A. Winter, Erin Stewart, Joseph M. Yabes, Peter Melby, Cody R. Butler, Mohamed I. Abdalla, Sandra G. Adams, Yemi Adebayo, Joseph Agnew, Saleem Ali, Gregory Anstead, Antonio Anzueto, Marichu Balmes, Jennifer Barker, Raymond Benavides, Velma Bible, Angela Birdwell, Stacy Braddy, Stephen Bradford, Heather Briggs, Jose A. Cadena Zuluaga, Judith Marin‐Corral, Jennifer J. Dacus, Patrick J. Danaher, Scott A. DePaul, Jill Dickerson, Jollynn Doanne, Samantha Elbel, Miguel Escalante, Corina Escamilla, Valerie Escamilla, Robert Farrar, David Feldman, Debra Flores, Julianne Flynn, Delvina Ford, Joanna D. Foy, Megan Freeman, Samantha Galley, Jessica Garcia, Maritza Garza, Sherraine Gilman, Melanie Goel, Jennifer Gomez, Varun K. Goyal, Sally Grassmuck, Susan Grigsby, Joshua Hanson, Brande Harris, Audrey Haywood, Joan M. Hecht, Cecilia Hinojosa, Tony T. Ho, Teri Hopkins, Aneela N. Hussain, Ali Jabur, Pamela Jewell, Thomas B. Johnson, Austin C. Lawler, Monica Lee, Chadwick S. Lester, Stephanie M. Levine, Haidee V. Lewis, Angel Louder, Charmaine Mainor, Rachel Maldonado, Celida Martinez, Yvette Martinez, Chloe Mata, Neil McElligott, Laura Medlin, Myra Mireles, Joanna Moreno, Kathleen Morneau, Julie Muetz, Samuel B. Munro, Charlotte Murray, Anoop Nambiar, Daniel Nassery, Robert Nathanson, Kimberly Oakman, Jane O’Rorke, Cheryl Padgett, Sergi Pascual‐Guardia, Marisa Patterson, Graciela L. Perez, Rogelio Perez, Jay I. Peters, Rogelio Perez III, Robert E. Phillips, Patrick B. Polk, Michael A. Pomager, Kristy J. Preston, Kevin C. Proud, Jacqueline A. Pugh, Michelle Rangel, Temple A. Ratcliffe, Renee L. Reichelderfer, Evan M. Renz, Jeanette Ross, Teresa Rudd, Maria E. Sanchez, Tammy Sanders, Kevin C. Schindler, David Schmit, Raj T. Sehgal, Claudio Solorzano, Nilam Soni, Win S. Tam, Edward J. Tovar, Sadie A. Trammell Velasquez, Anna R. Tyler, Anjuli Vasquez, Maria C. Veloso, Steven G. Venticinque, Jorge A. Villalpando, Melissa Villanueva, Lauren Villegas, Megan Walker, Andrew Wallace, Maria Wallace, Emily Wang, Stephanie Wickizer, Andreia Williamson, Andrea Yunes, Katharine H. Zentner, Azaneth Arellanes, Ashley B. Banfield, Stephanie N. Bolan‐Reding, Roxanne Colazo, Katherine S. DeLeon, Norma G. Diaz, Mario A. Garza, Raed Kadhume, Hue Mang, Erwin Paleracio, Robert F. Quitta, Laura J. Ramirez, Marzieh Salehi, Cynthia J. Varela   +176 more
wiley   +1 more source

Neonatal lupus erythematosus: an acquired autoimmune disease to be taken seriously. [PDF]

Ann Med
Sun W, Fu C, Jin X, Lei C, Zhu X.
europepmc   +1 more source

Age and Sex Effects on Blood Retrotransposable Element Expression Levels: Findings From the Population‐Based Rhineland Study

Aging Cell, EarlyView.
Retrotransposable element (RTE) expression increases with chronological and biological age and is negatively associated with heterochromatin regulators. Moreover, RTE expression shows sex‐specific differences, with higher levels in men and enrichment for immune‐related pathways.
Valentina Talevi, Hang‐Mao Lee, Dan Liu, Marc D. Beyer, Paolo Salomoni, Monique M. B. Breteler, N. Ahmad Aziz   +6 more
wiley   +1 more source

IgG glycosylation profiling of systemic lupus erythematosus using lectin microarray. [PDF]

Lupus Sci Med
Wu Y, Wang M, Hu C, Zhang S, Zhao J, Wang Q, Xu D, Tian X, Zhao Y, Zeng X, Li M.   +10 more
europepmc   +1 more source

A Guide to Screening for Autoimmune Diseases in Patients With Vulvar Lichen Sclerosus

Australasian Journal of Dermatology, EarlyView.
ABSTRACTBackgroundThe aetiology of vulvar lichen sclerosus (VLS) remains unknown. However, there is evidence that in addition to a genetic predisposition, autoimmunity contributes to the pathogenesis.ObjectivesThe objective of this study was to determine the prevalence of autoimmune disease and positive autoantibody serology in patients with VLS ...
Annabel Guttentag, Marlene Wijaya, Gayle O. Fischer, Angela Lee, Ken Liu, Rebecca Bronwyn Saunderson   +5 more
wiley   +1 more source

Prognostic insights from symptom clustering analysis in systemic lupus erythematosus. [PDF]

RMD Open
Le Tallec E, Bourg C, Bouzillé G, Belhomme N, Le Pabic E, Guillot S, Droitcourt C, Perlat A, Jouneau S, Sobanski V, Donal E, Lescoat A.   +11 more
europepmc   +1 more source

Wound, pressure ulcer, and burn guidelines (2023)―4: Guidelines for the management of connective tissue disease/vasculitis‐associated skin ulcers, third edition

The Journal of Dermatology, EarlyView.
Yoshihide Asano, Jun Asai, Takayuki Ishii, Yohei Iwata, Masanari Kodera, Chie Miyabe, Akihiko Uchiyama, Youichi Ogawa, Ken Okamura, Mari Kishibe, Yuta Koike, Yorihisa Kotobuki, Noriki Fujimoto, Takuya Miyagi, Yukie Yamaguchi, Ayumi Yoshizaki, Reiko Omori, Takeshi Nakanishi, Hiroshi Fujiwara, Takeo Maekawa, Sei‐ichiro Motegi, Yuichiro Yoshino, Minoru Hasegawa, Manabu Fujimoto, Takao Tachibana, Wound, Pressure Ulcer, and Burn Guidelines Drafting Committee (connective tissue disease/vasculitis group)   +27 more
wiley   +1 more source

Langerhans cells infiltration in lymph nodes of patients with systemic lupus erythematosus. [PDF]

Lupus Sci Med
Qian J, Li L, Lv J, Jiang Y, Ma Q, Pan H, Wei X, Yang Z, Yu S, Fan Y, Teng J, Yang C, Zhang A, Yang Y, Shi H.   +14 more
europepmc   +1 more source

Targeting the Galectin‐7/TRPM2/Zn2+/DRP‐1 Signaling Pathway: A Potential Therapeutic Intervention in the Pathogenesis of SJS/TEN

Allergy, EarlyView.
This study investigates the role of mitochondrial fission in keratinocyte apoptosis in blister fluid‐derived exosomes from patients with SJS/TEN, erythema multiforme, and in healthy individuals. Galectin‐7 is upregulated in exosomes of patients with SJS/TEN and shows a correlation with disease severity.
Chen Zhang, BingYu Pang, YiXin Luo, Zipeng Cao, Pei Qiao, ZhenLai Zhu, Hui Fang, JianKang Yang, ErLe Dang, ShengXian Shen, Pan Kang, Qingqing Jiao, Akito Hasegawa, Riichiro Abe, HongJiang Qiao, Gang Wang, Meng Fu   +16 more
wiley   +1 more source

Repair of Left Ventricular Pseudoaneurysm Due to Systemic Lupus Erythematosus. [PDF]

Braz J Cardiovasc Surg
Işık M, Görmüş N.
europepmc   +1 more source