Results 51 to 60 of about 33,131 (314)

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

Luteal phase support post IVF: individualized early stop [PDF]

Reproductive BioMedicine Online, 2015
While the need for progesterone-based luteal phase support is well documented, the required treatment duration is not well established, and a practitioners' survey showed a wide range of empiric stopping points. It is suggested that an early stop can be based on assessing endogenous luteal activity on the day of pregnancy test. To examine this approach,
Linoy, Segal, Tatiana, Breyzman, Shahar, Kol   +2 more
openaire   +2 more sources

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Lack of associations between female hormone levels and visuospatial working memory, divided attention and cognitive bias across two consecutive menstrual cycles [PDF]

, 2017
Background: Interpretation of observational studies on associations between prefrontal cognitive functioning and hormone levels across the female menstrual cycle is complicated due to small sample sizes and poor replicability. Methods: This observational
Egli, Marcel, Geraedts, Kirsten, Hengartner, Michael P., Ille, Fabian, Kruger, Tillmann H. C., Leeners, Brigitte, Mancini, Toni, Rã¶blitz, Susanna, Saleh, Lanja, Schippert, Cordula, Spanaus, Katharina, Tronci, Enrico, Zhang, Yuangyuang   +12 more
core   +4 more sources

Morphometric analysis of postnatal lung development in the gray short‐tailed opossum (Monodelphis domestica): An ultrastructural study

The Anatomical Record, EarlyView.
Abstract An ultrastructural morphometric analysis of the postnatal development of the lung in the gray short‐tailed opossum (Monodelphis domestica) has been conducted to evaluate the morphofunctional status of this poorly developed marsupial lung immediately following parturition.
Kirsten Ferner
wiley   +1 more source

Abnormal expression of p27kip1 protein in levator ani muscle of aging women with pelvic floor disorders – a relationship to the cellular differentiation and degeneration [PDF]

, 2001
BACKGROUND: Pelvic floor disorders affect almost 50% of aging women. An important role in the pelvic floor support belongs to the levator ani muscle. The p27/kip1 (p27) protein, multifunctional cyclin-dependent kinase inhibitor, shows changing expression
A Bukovsky, A Bukovsky, A Bukovsky, A Bukovsky, A Bukovsky, A Shafik, A Shafik, Antonin Bukovsky, BM-Praeger Stanulis, Bridgett Asbury, CY Chu, D Failes, F Beersiek, H Toyoshima, I Overlie, IT Bernstein, J Yeargin, Jeffrey B Brown, JO DeLancey, JO DeLancey, JQ Tian, JT Benson, K Kenton, K Polyak, L Guth, LT Bjornsdottir, LT Brubaker, M Jozwik, M Loden, M Sandri, MA Habiba, Maria Cekanova, Michael R Caudle, N Santoro, P Copas, P Kjolhede, PA Norton, PJ Blakeman, Pleas Copas, PP McKenzie, Robert F Elder, RV Lloyd, S Fujieda, SA Gilpin, SD Zabludoff, Stephanie B Cross, Stuart E Van Meter, Tamara Dassanayake, Y Katayose   +48 more
core   +4 more sources

Luteal Phase Support in In Vitro Fertilization [PDF]

Seminars in Reproductive Medicine, 2015
It has been well demonstrated that luteal phase physiology is disrupted in in vitro fertilization (IVF) cycles conducted with either gonadotropin-releasing hormone (GnRH) agonists or antagonists, and that supplementation of the luteal phase with either exogenous progesterone or human chorionic gonadotropin (hCG) is necessary to optimize IVF cycle ...
openaire   +2 more sources

Unraveling ovarian histology: The key morphological aspects that spur the development of the Fossa ovarii in equine

The Anatomical Record, EarlyView.
Abstract The equine ovary exhibits unique structural and developmental features that distinguish it from those of other domestic species, including the presence of an ovulation fossa and an inversion of cortical and medullary layers. This study aimed to investigate the morphostructural development of the equine fetal ovary, with particular emphasis on ...
Laura Ver Goltz, Silvio Pires Gomes, Bruno Cesar Schimming, Fabio Cesar Magioli Abdala, Maria Angélica Miglino, Tais Harumi de Castro Sasahara   +5 more
wiley   +1 more source

Serum progesterone concentration on pregnancy test day might predict ongoing pregnancy after controlled ovarian stimulation and fresh embryo transfer

Frontiers in Endocrinology, 2023
Progesterone (P4) is essential for pregnancy. A controlled ovarian stimulation (COS) leads to a iatrogenic luteal defect that indicates a luteal phase support (LPS) at least until pregnancy test day. Some clinicians continue the LPS until week 8 or later,
Marie Duport Percier, Sophie Brouillet, Sophie Brouillet, Caroline Mollevi, Martha Duraes, Tal Anahory, Noemie Ranisavljevic   +6 more
doaj   +1 more source

Freeze-all policy versus luteal phase support with low dose of human chorionic gonadotrophin for high-responder patients undergoing intracytoplasmic sperm injection on pregnancy outcomes: a retrospective cohort observational study [PDF]

, 2022
Ehab Elhelw, Ahmed G. Serour, Mahmoud Salah Mahmoud Rady, Ahmed Abdeltawab   +3 more
openalex   +1 more source