Results 11 to 20 of about 483,323 (270)

Luteinizing Hormone Releasing Hormone/Galactose Core/Lipopeptide

Molbank, 2015
A self-adjuvanting vaccine candidate comprising four copies of luteinizing hormone releasing hormone (LHRH), a galactose carrier/core and lipoamino acid based adjuvant was synthesized in 21% yield by a solid phase peptide synthesis, carbohydrate and Boc ...
Pavla Simerska, Hoi Ling Lai, Istvan Toth   +2 more
doaj   +2 more sources

Dose-Response relationship of luteinizing hormone to luteinizing hormone—releasing hormone in man [PDF]

Journal of Clinical Investigation, 1971
In previous clinical studies with highly purified porcine luteinizing hormone-releasing hormone (LH-RH), administration of the somewhat arbitrarily chosen doses of 700-1500 mug resulted in increased serum levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
A J, Kastin, A V, Schally, C, Gual, A R, Midgley, M C, Miller, A, Cabez   +5 more
openaire   +4 more sources

Stereoisomers of luteinizing hormone-releasing hormone

Biochemical and Biophysical Research Communications, 1974
Summary Six decapeptide analogs of the luteinizing hormone-releasing hormone (LH-RH) were prepared with the D-isomers of pyroglutamic acid, histidine, tryptophan, tyrosine, leucine, and arginine successively replacing the corresponding L-amino acids of the hormone. [D-pGlu 1 ]-LH-RH and [D-His 2 ]-LH-RH had appreciable LH-releasing activities, 8% and
Y, Hirotsu, D H, Coy, E J, Coy, A V, Schally   +3 more
openaire   +3 more sources

Serological biomarker models composed of luteinizing hormone, kisspeptin, vitamin D and estradiol, and their clinical test value in girls [PDF]

Jornal de Pediatria
Objective: Central precocious puberty (CPP) may lead to premature pubertal onset. While the GnRH stimulation test remains the gold standard, its invasive nature and prolonged procedure limit clinical utility, particularly in pediatric populations ...
Mingyu Shao, Zhiyi Jia, Tongtong Liu, Xiaopeng Zhang   +3 more
doaj   +2 more sources

A delay differential equation mathematical model for the control of the hormonal system of the hypothalamus, the pituitary and the testis in man [PDF]

, 2008
In this paper we develop previously studied mathematical models of the regulation of testosterone by luteinizing hormone and luteinizing hormone release hormone in the human body. We propose a delay differential equation mathematical model which improves
, Sultan Qaboos University, Oman (Funder), Khan, Q.J.A., Greenhalgh, D., Greenhalgh, David, Khan, Qamar J. A., Khan, Qamar, Sultan Qaboos University, Oman (Funder)   +6 more
core   +4 more sources

Introduction: luteinizing hormone for life’s journey [PDF]

Reproductive Biology and Endocrinology
Carlo Alviggi, Sandro C. Esteves, Robert Fischer, Peter Humaidan   +3 more
doaj   +2 more sources

Frequency of the allelic variant (Trp8Arg/Ile15Thr) of the luteinizing hormone gene in a Brazilian cohort of healthy subjects and in patients with hypogonadotropic hypogonadism [PDF]

Clinics, 2005
PURPOSE: To evaluate the frequency of allelic variant Trp8Arg/Ile15Thr in the luteinizing hormone beta-subunit gene in a Brazilian population of healthy subjects and in patients with hypogonadotropic hypogonadism.
Karina Berger, Ana Elisa Correia Billerbeck, Elaine Maria Frade Costa, Luciani Silveira Carvalho, Ivo Jorge Prado Arnhold, Berenice Bilharinho Mendonca   +5 more
doaj   +1 more source

Advanced bone age as an indicator facilitates the diagnosis of precocious puberty

Jornal de Pediatria, 2018
Objective: Diagnosis of central precocious puberty has always been challenging in clinical practice. As an important method in the diagnosis of central precocious puberty, luteinizing hormone-releasing hormone stimulation test is complex and time ...
Yue-Qin Xu, Gui-Mei Li, Yan Li
doaj   +3 more sources

A case of hypogonadtropic hypogonadism due to hypophysitis discovered by secondary male infertility

IJU Case Reports, 2023
Introduction The main causes of secondary male infertility are varicocele and aging. It is rarely caused by adult‐onset hypopituitarism. The onset of hypopituitarism is often due to brain tumors, trauma, surgery, or congenital disorders.
Masatoshi Konishi, Yoko Maegawa, Masaru Tani, Toshihisa Asakura, Yujiro Hayashi, Yoichi Kakuta, Koichi Tsutahara, Kazuhiko Komori, Tetsuya Takao   +8 more
doaj   +1 more source

Pituitary response to luteinizing hormone-releasing hormone in women with variant luteinizing hormone [PDF]

European Journal of Endocrinology, 2000
OBJECTIVE: To assess the LH response of the pituitary gland to GnRH stimulation in healthy women with a mutant beta-subunit (Trp8 to Arg8 and Ile15 to Thr15). DESIGN: Clinical study. PATIENTS: We studied 40 healthy non-pregnant Japanese women of known zygosity for the LH beta-subunit gene (3 homozygotes for the mutant gene, 17 heterozygotes, and 20 ...
K, Takahashi, H, Kurioka, T, Ozaki, H, Kanasaki, K, Miyazaki, K, Karino   +5 more
openaire   +2 more sources