Luteinizing Hormone Releasing Hormone/Galactose Core/Lipopeptide
A self-adjuvanting vaccine candidate comprising four copies of luteinizing hormone releasing hormone (LHRH), a galactose carrier/core and lipoamino acid based adjuvant was synthesized in 21% yield by a solid phase peptide synthesis, carbohydrate and Boc ...
Pavla Simerska +2 more
doaj +2 more sources
Differentiation of adult-type Leydig cells occurs in gonadotrophin-deficient mice [PDF]
During mammalian testis development distinct generations of fetal and adult Leydig cells arise. Luteinising hormone (LH) is required for normal adult Leydig cell function and for the establishment of normal adult Leydig cell number but its role in the ...
Baker, P.J. +4 more
core +9 more sources
A delay differential equation mathematical model for the control of the hormonal system of the hypothalamus, the pituitary and the testis in man [PDF]
In this paper we develop previously studied mathematical models of the regulation of testosterone by luteinizing hormone and luteinizing hormone release hormone in the human body. We propose a delay differential equation mathematical model which improves
, Sultan Qaboos University, Oman (Funder) +6 more
core +4 more sources
Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner. [PDF]
The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre +3 more
core +3 more sources
Characteristics of the vaginal microbiome in women with premature ovarian insufficiency
Purpose To investigate the relationship between vaginal microbial community structure and premature ovarian insufficiency (POI). Methods Twenty-eight women with POI and 12 healthy women were recruited at Shenzhen Maternity and Child Healthcare Hospital ...
Jiaman Wu +5 more
doaj +1 more source
Transcriptional Profiling of Luteinizing Hormone Receptor-Deficient Mice Before and after Testosterone Treatment Provides Insight into the Hormonal Control of Postnatal Testicular Development and Leydig Cell Differentiation [PDF]
Luteinizing hormone (LH) is a key regulator of male fertility through its effects on testosterone secretion by Leydig cells. Transcriptional control of this is, however, currently poorly understood.
Affara, Nabeel +5 more
core +1 more source
Hypothalamic KiSS1/GPR54 Gene Expressions and Luteinizing Hormone Plasma Secretion in Morphine Treated Male Rats [PDF]
Background: The inhibitory effects of morphine and the stimulatory influence of kisspeptin signaling have been demonstrated on gonadotropin releasing hormone (GnRH)/luteinizing hormone (LH) release.
Homayoun Khazali +2 more
doaj +1 more source
Background Our objective was to investigate luteinizing hormone, follicle-stimulating hormone, testosterone, and androstenedione as predicitve markers for ovulation after laparoscopic ovarian drilling.
Mayerhofer Klaus +6 more
doaj +1 more source
Plasticity of Anterior Pituitary Gonadotrope Cells Facilitates the Pre-Ovulatory LH Surge
Gonadotropes cells located in the anterior pituitary gland are critical for reproductive fitness. A rapid surge in the serum concentration of luteinizing hormone (LH) secreted by anterior pituitary gonadotropes is essential for stimulating ovulation and ...
Colin M. Clay +2 more
doaj +1 more source
Differential expression and functional characterization of luteinizing hormone receptor splice variants in human luteal cells : Implications for luteolysis [PDF]
The human LH receptor (LHR) plays a key role in luteal function and the establishment of pregnancy through its interaction with the gonadotropins LH and human chorionic gonadotropin.
Dickinson, Rachel E +4 more
core +1 more source

