Results 81 to 90 of about 149 (149)

Cryptorchidism: Novel genetic insights into CCDC149 mutations

Andrology, EarlyView.
Abstract Background Cryptorchidism, characterized by the failure of one or both testes to descend into the scrotum, is a common congenital condition that can lead to infertility and increased risk of testicular cancer. CCDC149, a coiled‐coil domain‐containing protein, has been implicated in various developmental processes, but its role in the male ...
Shengrong Du, Shan Xu, Lei Yang, Yan Ye, Yuhan Wu, Ziyun Xiao, Xiuqing Dong, Wenliang Yao, Hua Li   +8 more
wiley   +1 more source

Endocrine Abnormalities and Growth Pattern in Single Large‐Scale Mitochondrial DNA Deletion Syndromes

Acta Paediatrica, EarlyView.
ABSTRACT Aim To assess the prevalence of endocrine disorders and investigate growth patterns in single large‐scale mitochondrial DNA deletion syndromes (SLSMDs). Methods A retrospective study of all children with SLSMD who attended Sheba Medical Center, Israel, from February 2017 to September 2024.
Ayman Daka, Einat Lahav, Omer Bar Yosef, Yoav Bolkier, Yael Levy‐Shraga, Yair Anikster, Elad Jacoby, Noah Gruber   +7 more
wiley   +1 more source

Treatment With Inhaled Nitric Oxide and General Intelligence in Preterm Children in Two European Cohorts

Acta Paediatrica, EarlyView.
ABSTRACT Aim To investigate whether treatment with inhaled nitric oxide is associated with cognitive performance at age 5–6 years in preterm‐born children. Methods We analysed preterm children from two large European cohort studies, the German Neonatal Network (GNN) (N = 3606) and the French EPIPAGE‐2 cohort (N = 2579) admitted to neonatal care and ...
Nicole Tsalacopoulos, Valérie Benhammou, Laetitia Marchand‐Martin, Véronique Pierrat, Pierre‐Yves Ancel, Armita Shahesmaeilinejad, Viktoria Rücker, Vincent Prevot, Konstantina Chachlaki, Christoph Härtel, Wolfgang Göpel, Juliane Spiegler, on behalf of the miniNO Consortium   +12 more
wiley   +1 more source

Moderate Day‐To‐Day Variation in First‐Morning Urine Total Luteinizing Hormone Levels Supports the Use of a Single Determination to Identify Imminent Puberty

Clinical Endocrinology, Volume 102, Issue 5, Page 578-588, May 2025.
ABSTRACT Objectives We aimed to study the daily variation in first‐morning urinary total luteinizing hormone (U‐LH) determination and validate it as a noninvasive method for analyzing age‐ and pubertal stage‐related changes in LH immunoreactivity (LH‐ir) levels to predict imminent onset of central puberty.
And Demir, Matti Hero, Anders Juul, Katharina M. Main   +3 more
wiley   +1 more source

RADIOIMMUNOASSAY FOR EQUINE LUTEINIZING HORMONE [PDF]

Reproduction, 1973
B. C. Wentworth, N. L. First, A. S. Anand, K. W. Thompson   +3 more
openaire   +3 more sources

Clinical Presentation of Congenital Hypopituitarism: Lessons From a Large Academic Centre

Clinical Endocrinology, Volume 102, Issue 6, Page 649-655, June 2025.
ABSTRACT Objective Pituitary hormone deficiencies are associated with considerable morbidity, yet the variability of presentation and evolution of congenital hypopituitarism remains unexplored. This study investigated differences in presentation of congenital isolated pituitary hormone deficiency (cIPHD) versus congenital multiple pituitary hormone ...
Jennifer M. Ladd, Amy L. Pyle‐Eilola, Leena Mamilly, Monika Chaudhari, Rohan K. Henry   +4 more
wiley   +1 more source

Systematic Review and Meta‐Analysis on the Prevalence of Radiotherapy‐Induced Hypopituitarism in Adults With Primary Non‐Pituitary Brain Tumours

Clinical Endocrinology, Volume 102, Issue 6, Page 683-698, June 2025.
ABSTRACT Context It is well recognised there is a high prevalence of pituitary dysfunction in childhood brain tumours survivors who are treated with radiotherapy. In contrast, the potential for survivors of brain tumours arising in adulthood to develop radiotherapy‐induced hypopituitarism may be underestimated.
Darran Mc Donald, Maria Tomkins, Liam O'Connell, David Fitzpatrick, Clare Faul, Michael W. O'Reilly, Kathleen Bennett, Mark Sherlock   +7 more
wiley   +1 more source

Determination of Androgen Bioactivity by an In Vitro Assay During Pubertal Transition in Healthy Boys

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To describe the bioactivity of circulating androgens during pubertal transition as determined by an in vitro bioassay assessing androgen receptor (AR) activation, and to compare these findings with circulating concentrations of total testosterone (total T) measured by LC‐MS/MS.
Andrés Felipe Ø. Fritzbøger, Lise Aksglaede, Trine Holm Johannsen, Dirk Vanderschueren, Leen Antonio, Frank Claessens, Katrine Harpelunde Poulsen, Anne Jørgensen, Jørgen Holm Petersen, Anna‐Maria Andersson, Anders Juul   +10 more
wiley   +1 more source

Delayed Bone Maturation and Extended Growth Phase as Distinctive Features of 17α‐Hydroxylase/17,20‐Lyase Deficiency: A Retro‐Prospective Study of a Large Patient Cohort

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Worldwide, combined 17‐hydroxylase/17,20‐lyase deficiency (CYP17D) is a rare form of congenital adrenal hyperplasia, but it is the second most prevalent type in Brazil. An absence of sexual differentiation and hypergonadotropic hypogonadism arise from a reduction in the usual pattern of sex steroid formation in the adrenals and ...
Rafaela Fontenele, Flávia A. Costa‐Barbosa, Marivânia Costa‐Santos, Rafael L. Batista, Lívia M. Mermejo, Berenice B. Mendonça, Margaret de Castro, Gil Guerra‐Júnior, Claudio E. Kater, Brazilian Congenital Adrenal Hyperplasia Multicenter Study Group (BCAHMSG)   +9 more
wiley   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source