Long‐term repeated immunisation against GnRH resulted in the absence of active spermatogenesis and may lead to irreversible infertility in dwarf bucks and baboons. Histological examination revealed a marked reduction of the seminiferous tubular lumen, complete depletion of germ cells, germ cell vacuolization and tubular hyalinization.
Teresa Ferrín +8 more
wiley +1 more source
Correction to: Elevated luteinizing hormone receptor signaling or selenium treatment leads to comparable changes in adrenal cortex histology and androgen-AR/ZIP9 signaling. [PDF]
Wieczorek J +7 more
europepmc +1 more source
ABSTRACT Objective Women with polycystic ovary syndrome (PCOS) exhibit a substantially increased risk of miscarriage, yet the underlying mechanisms remain inadequately understood. This study aimed to investigate whether specific gut microbial dysbiosis and metabolic disturbance are associated with and may potentially contribute to endometrial ...
Mengyu Jing +9 more
wiley +1 more source
CNS luteinizing hormone receptor activation rescues ovariectomy-related loss of spatial memory and neuronal plasticity. [PDF]
Blair JA, Bhatta S, Casadesus G.
europepmc +1 more source
Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats. [PDF]
Bakhtyukov AA +8 more
europepmc +1 more source
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos +4 more
wiley +1 more source
Elevated luteinizing hormone receptor signaling or selenium treatment leads to comparable changes in adrenal cortex histology and androgen-AR/ZIP9 signaling. [PDF]
Wieczorek J +7 more
europepmc +1 more source
Abstract The pattern of gonadotropin‐releasing hormone (GnRH) release controls reproduction in vertebrates and is regulated by feedback from the gonads. Evidence is accumulating that steroid‐sensitive hypothalamic arcuate kisspeptin–neurokinin B–dynorphin (KNDy) neurons drive GnRH pulses.
R. Anthony DeFazio +4 more
wiley +1 more source
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund +5 more
wiley +1 more source
Identification and Characterization of a Luteinizing Hormone Receptor (LHR) Homolog from the Chinese Mitten Crab Eriocheir sinensis. [PDF]
Yuan LJ +4 more
europepmc +1 more source

