Results 181 to 190 of about 34,840 (229)
Some of the next articles are maybe not open access.
Human pineal luteinizing hormone receptors
Biotechnic & Histochemistry, 2002The presence of luteinizing hormone receptors in human pineal glands from five females and three males, ranging in age from 61-89 yr, was examined by in situ hybridization and immunocytochemistry. The results demonstrated the presence of these receptors at the mRNA and protein levels in all the pineal glands examined.
K P, Bhatnagar +3 more
openaire +2 more sources
Luteinizing Hormone Receptors in Luteinized Rat Ovaries
1973It has been demonstrated that radioiodinated HCG and LH are accumulated in vivo by mouse and rat ovaries (1–4). These observations suggested the existence of specific receptor sites for gonadotropic hormone in this target tissue. Recently, the existence of specific receptors for LH and HCG have been reported in slices of luteinized rat ovaries (5) and ...
C Y, Lee, R J, Ryan
openaire +2 more sources
Human placental receptors for luteinizing hormone releasing hormone
Biochemical and Biophysical Research Communications, 1981Abstract Plasma membrane preparations of human term placenta bound 125I-labelled luteinizing hormone releasing hormone (LHRH) agonist with high affinity (KA = 5.5×107M−1) and specificity. Native LHRH competed for binding with the same affinity (KA = 6.2 × 107 M−1) whereas fragments of the LHRH agonists, oxytocin, somatostatin and TRH gave no or ...
A J, Currie, H M, Fraser, R M, Sharpe
openaire +2 more sources
Hormonal Regulation of Testicular Luteinizing Hormone and Prolactin Receptors
Endocrinology, 1981The effects of gonadotropic stimulation on testicular LH and PRL receptors were examined in the absence and presence of elevated serum PRL levels. In adult male rats, the administration of ovine LH (oLH) caused an increase in both PRL and LH receptors within 40–120 min.
V, Chan +3 more
openaire +2 more sources
‘Spare’ Luteinizing Hormone Receptors: Facts and Fiction
Trends in Endocrinology & Metabolism, 2018It is common opinion that maximal activation of luteinizing hormone (LH)-dependent steroidogenic signal occurs at
Casarini Livio +3 more
openaire +3 more sources
Structure‐Function Relationships of the Luteinizing Hormone Receptor
Annals of the New York Academy of Sciences, 2005Abstract: Of the 800‐900 genes in the human genome that appear to encode G‐protein‐coupled receptors (GPCRs), two are known to encode receptors that bind the three heterodimeric human gonadotropins, luteinizing hormone (LH), chorionic gonadotropin (CG), and follicle‐stimulating hormone (FSH).
D. PUETT +6 more
openaire +3 more sources
THE LUTEINIZING HORMONE RECEPTOR
Annual Review of Physiology, 1995▪ Abstract The luteinizing hormone receptor (LHR) is a member of the subfamily of glycoprotein hormone receptors within the superfamily of G protein–coupled receptor (GPCR)/seven-transmembrane domain receptors. Over the past eight years, major advances have been made in determining the structure and function of the LHR and its gene.
openaire +2 more sources
Luteinizing hormone receptor mutations and sex differentiation
European Journal of Endocrinology, 1996Themmen APN, Brunner HG. Luteinizing hormone receptor mutations and sex differentiation. Eur J Endocrinol 1996;134:533–40. ISSN 0804–4643 Mutations in the luteinizing hormone (LH) receptor gene have been found in patients with abnormalities in their sexual differentiation.
Themmen, A.P.N., Brunner, H.G.
openaire +3 more sources
Structure and regulation of the luteinizing hormone receptor gene
The Journal of Steroid Biochemistry and Molecular Biology, 1995Studies of the mechanisms controlling the expression of the rat luteinizing hormone receptor gene were pursued by characterization of the gene structure and identification of regulatory protein binding domains in the 5'-non-coding region of the gene and of 3' non-coding functional domains responsible for generation of the major mRNA forms.
M L, Dufau +3 more
openaire +2 more sources
Activation of the luteinizing hormone receptor in the extracellular domain
Molecular and Cellular Endocrinology, 2003Glycoprotein hormone receptors have ligand-binding ectodomains consisting of leucine-rich repeats, followed by a conserved cysteine-rich hinge region to the seven transmembrane (TM) region. Based on constitutively active mutations at Ser-281 in the hinge region of the thyroid-stimulating hormone receptor, we mutated the conserved serine in the ...
Koji, Nakabayashi +3 more
openaire +2 more sources