Characterization of blood group variants in an Omani population by comparison of whole genome sequencing and serology. [PDF]
Abstract Background Although blood group variation was first described over a century ago, our understanding of the genetic variation affecting antigenic expression on the red blood cell surface in many populations is lacking. This deficit limits the ability to accurately type patients, especially as serological testing is not available for all ...
Haffener PE +7 more
europepmc +2 more sources
Erythrocyte Alloimmunization and Transfusion Strategies in Sickle Cell Disease: A Single-Center Analysis [PDF]
Abdulaziz Yusuf,1,2 Abrar Ahmad,1 Hesham A El-Beshbishy,3 Heba Badie Gong,3 Chahed Walid Chahdah,3 Tahani Bakhsh4 1Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; 2Blood Bank Department, Dr. Soliman Fakeeh
Yusuf A +5 more
doaj +2 more sources
A cross-sectional pilot study to estimate the frequency of minor blood group alleles and phenotypes in RhD-negative North Indian blood donors by DNA microarray analysis [PDF]
INTRODUCTION: There are scarce data on Indian blood donors with respect to blood group phenotypes using molecular diagnostic modalities. Hence, we planned to estimate frequencies of blood group alleles/phenotypes using DNA microarray analysis in the ...
Gita Negi +4 more
doaj +2 more sources
Resolving the Interference of Anti-CD38 Antibodies on Blood Compatibility Assays Using CD38 "Baitbodies" Approach. [PDF]
Blood transfusion safety depends on swift blood compatibility testing. Alloantibodies recognizing these blood group antigens determine blood compatibility, and the transfusion of incompatible blood can lead to life‐threatening hemolytic transfusion reactions.
Gnann DC +3 more
europepmc +2 more sources
Amani Y Owaidah,1 Noor M Naffaa,1 Arwa Alumran,2 Faisal Alzahrani1 1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 2Department of Health Information ...
Owaidah AY +3 more
doaj +4 more sources
Background: This is the first study on phenotype frequencies of various blood group systems in blood donors of south Gujarat, India using conventional tube technique.
Manoj A Kahar, Rajnikant D Patel
doaj +3 more sources
Targeted next-generation sequencing and long-read HiFi sequencing provide novel insights into clinically significant KLF1 variants [PDF]
Background Krüppel-like factor 1 (KLF1), a crucial erythroid transcription factor, plays a significant role in various erythroid changes and haemolytic diseases.
Luyi Ye +7 more
doaj +2 more sources
Objective To investigate the gene frequency and polymorphism of RBC blood group systems in RhD negtive population in Hunan, so as to lay a foundation for clinical blood transfusion and construction of multiple rare blood group database.
Binbin ZOU +4 more
doaj +1 more source
An overview about erythrocyte membrane [PDF]
© 2010 – IOS Press and the authors. All rights reservedIn the sixties and seventies, erythrocytes or red blood cells (RBCs) were extensively studied. Much has been learnt particularly concerning their metabolism and gas transporter function. In the past
Oliveira, Sofia de, Saldanha, Carlota
core +1 more source
Review: the Lutheran blood group system–1991 [PDF]
Abstract The Lutheran blood group system, comprised of 18 antigens with four pairs of alleles at closely linked loci, is complex. This article outlines current knowledge of the Lutheran system with special reference to recent serologic, Immunochemical, and clinical findings.
openaire +2 more sources

