Results 91 to 100 of about 56,397 (258)

High exposure to hepatitis C virus in Saravan, southern Laos; identification of several risk practices

open access: yesThe Lancet Regional Health. Western Pacific, 2022
Antony P. Black   +5 more
doaj   +1 more source

Spatial distribution of organics in the Horsehead nebula: Signposts of chemistry driven by atomic carbon

open access: yesAstronomy & Astrophysics
Complex organic molecules (COMs) are considered essential precursors to prebiotic species in the interstellar and circumstellar medium. Despite their astrobiological relevance, many aspects of the formation of COMs remain unclear, particularly the role ...
Hernández-Vera Claudio   +12 more
doaj   +1 more source

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

open access: yesAdvanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong   +6 more
wiley   +1 more source

Studi Intensitas Pencahayaan Terhadap Puncak Produksi Ayam Petelur Fase Layer di UD. Mahakarya Farm Banyuwangi

open access: yesJurnal Ilmu Peternakan Terapan, 2019
The objective of this case study was to evaluate good lighting levels in laying hens. The data were collected for three months at UD. Mahakarya Farm Banyuwangi. A total of 4.400 heads of layer chicken were used in this study.
Erfan Kustiawan   +3 more
doaj  

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

open access: yesAdvanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang   +10 more
wiley   +1 more source

Efeito da intensidade luminosa sobre o crescimento de juvenis do linguado Paralichthys orbignyanus

open access: yesBoletim do Instituto de Pesca, 2018
A maioria dos peixes necessita de ambiente com intensidade luminosa mí­­nima para o seu desenvolvimento e crescimento. O objetivo do presente estudo foi avaliar o efeito da intensidade luminosa sobre o crescimento de juvenis do linguado Paralichthys ...
Claudio Abdon Alvarez-Verde   +2 more
doaj  

Field‐Free Spin‐Splitting‐Torque Driven Stochastic Neuron Mimicking the Neuromorphic Imagination for High‐Performance Recognition

open access: yesAdvanced Science, EarlyView.
The human brain's imagination, which enables autonomous driving hazard avoidance by completing missing visual information, relies on Gaussian‐stochastic neuron. We report the altermagnetic RuO2 spintronic neurons integrating field‐free switching and intrinsic Gaussian stochasticity, building an all‐spin ANN for high‐quality image repairing and high ...
Junwei Zeng   +9 more
wiley   +1 more source

PANX2 Suppresses Lung Adenocarcinoma Progression by Inducing Disulfidptosis and Enhancing Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen   +7 more
wiley   +1 more source

Synergistic Probe Combining Lysosome Anchoring and Tumor Defense System Targeting for Precise Tumor Visualization

open access: yesAdvanced Science, EarlyView.
A new generation of high‐precision fluorescent probes based on the lysosomal characteristics in tumor metabolic reprogramming and overexpressed tumor markers. The probe (CN‐D‐GGT) selectively label cancer cells in co‐culture systems and distinguish tumor lesions from inflamedand normal tissues in vivo, enabling precise tumor imaging.
Yang Shen   +6 more
wiley   +1 more source

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