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Bacterial quorum-sensing systems in cell-cell communication. [PDF]
FEMS Microbiol RevXu KZ +5 more
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Targeting quorum sensing: natural product-based inhibition and quenching for antimicrobial strategies. [PDF]
Future MicrobiolKhan MA, Wang S, Zhu H.
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Role and Regulation of Bacterial LuxR-Like Regulators
Journal of Cellular Biochemistry, 2011LuxR transcriptional regulator is a key player in Quorum Sensing (QS), coordinates the expression of a variety of genes, including those encoding virulence factors and antibiotics biosynthesis, motility, nodulation, plasmid transfer, bioluminescence, and biofilm formation. The characteristics and roles of this family, especially those of Mycobacterium,
Jianping Xie
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Roles of LuxR-family regulators in the biosynthesis of secondary metabolites in Actinobacteria
World Journal of Microbiology and Biotechnology, 2022Actinobacteria are well-known Gram-positive bacteria that produce approximately two-thirds of microbial bioactive natural products (NPs) through secondary metabolism. Usually, genes involved in the biosynthesis of NPs in actinobacteria are clustered, and their expression is regulated by an elaborate and stringent regulatory network formed by diverse ...
Zhangqun, Li, Xiaofang, Li, Haiyang, Xia
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Characterization of a LuxR repressor for 3,17β-HSD in Comamonas testosteroni ATCC11996
Chemico-Biological Interactions, 20213,17β-Hydroxysteroid dehydrogenase in Comamonas testosteroni (C. testosteroni) is a key enzyme involved in the degradation of steroid compounds. Recently, we found that LuxR is a negative regulator in the expression of the 3,17β-HSD gene. In the present work, we cultured wild-type and LuxR knock-out mutants of C.
Ye, Ji +5 more
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Noise and kinetics of LuxR positive feedback loops
Biochemical and Biophysical Research Communications, 2007We have previously reported the design and construction of positive feedback loops (PFLs) based on the LuxI-LuxR quorum-sensing system that can be used as modular transcriptional regulatory units for the construction of complex artificial genetic circuits.
Daniel J, Sayut +2 more
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Quorum Sensing and LuxR Solos in Photorhabdus
2016Bacterial communication via small diffusible molecules to mediate group-coordinated behaviour is commonly referred to as 'quorum sensing'. The prototypical quorum sensing system of Gram-negative bacteria consists of a LuxI-type autoinducer synthase that produces acyl-homoserine lactones (AHLs) as signals and a LuxR-type receptor that detects the AHLs ...
Sophie, Brameyer, Ralf, Heermann
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The LuxR Regulator Protein Controls Synthesis of Polyhydroxybutyrate in Vibrio harveyi
BBA - Proteins and Proteomics, 1998The LuxR regulatory protein of Vibrio harveyi has been shown to control synthesis of polyhydroxybutyrate (PHB) as well as luminescence so as to occur at high cell density, suggesting that it is a general regulatory protein. Mutants defective in the production of LuxR (D1, D34, and MR1130) were found to be missing PHB, whose synthesis could be restored ...
Carol M Miyamoto +2 more
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Functional analysis of a novel repressor LuxR in Comamonas testosteroni
Chemico-Biological Interactions, 2017Comamonas testosteroni (C. testosteroni) ATCC11996 is a gram negative bacterium which can use steroid as a carbon and energy source. 3,17β-hydroxysteroid dehydrogenase (3,17β-HSD) is a key enzyme for the degradation of steroid hormones in C. testosteroni.
Ye, Ji +4 more
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