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Functional analysis of a novel repressor LuxR in Comamonas testosteroni
Chemico-Biological Interactions, 2017Comamonas testosteroni (C. testosteroni) ATCC11996 is a gram negative bacterium which can use steroid as a carbon and energy source. 3,17β-hydroxysteroid dehydrogenase (3,17β-HSD) is a key enzyme for the degradation of steroid hormones in C. testosteroni.
Ye, Ji +4 more
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Regulation of aureofuscin production by the PAS-LuxR family regulator AurJ3M
Enzyme and Microbial Technology, 2020aurJ3M(GenBank:EU697915.1), a 579 bp gene, whose deduced product (192 amino acid) was found to have amino acid sequence homology with some bacterial regulatory proteins. Computer-assisted analysis showed that AurJ3M is PAS-LuxR family regulatory protein, it combines a PAS domain with a helix-turn-helix (HTH) motif of the LuxR type.
Jing Yang +4 more
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[Advances in quorum-sensing LuxR solos in bacteria].
Wei sheng wu xue bao = Acta microbiologica Sinica, 2018Quorum-sensing (QS) involved in the production of N-Acylhomoserine lactones (AHLs) is a universal way of communication of gram-negative bacteria. Complete AHL-QS system includes pairs of AHLs synthase belonging to LuxI family and cognate LuxR-family AHLs sensor-regulator.
Xiaofeng, Ye, Junli, Zhu, Haifeng, Wang
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Evolution of LuxR solos in bacterial communication: receptors and signals
Biotechnology Letters, 2019Cell-cell communication in bacteria needs chemical signals and cognate receptors. Many Gram-negative bacteria use acyl-homoserine lactones (AHLs) and cognate LuxR-type receptors to regulate their quorum sensing (QS) systems. The signal synthase-receptor (LuxI-LuxR) pairs may have co-evolved together.
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PAS-LuxR transcriptional control of filipin biosynthesis in S. avermitilis
Applied Microbiology and Biotechnology, 2014The DNA region encoding the filipin gene cluster in Streptomyces avermitilis (pte) contains a PAS-LuxR regulatory gene, pteF, orthologue to pimM, the final pathway-specific positive regulatory protein of pimaricin biosynthesis in Streptomyces natalensis. Gene replacement of the gene from S.
Vicente, Cláudia M +5 more
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New insights into the regulatory mechanisms of the LuxR family of quorum sensing regulators
Analytical and Bioanalytical Chemistry, 2006Bacteria use small signal molecules, referred to as autoinducers, in order to monitor their population density and coordinate gene expression in a process named quorum sensing. In Gram-negative bacteria, acylated homoserine lactones are the most common autoinducer used for cell-to-cell communication.
William, Nasser, Sylvie, Reverchon
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Transcriptional Control during Quorum Sensing by LuxR and LuxR Homologues
2014Quorum sensing is a mechanism used by many proteobacteria to regulate expression of target genes in a population-dependent manner. The quorum sensing system of Vibrio fischeri activates the luminescence (lux) operon when the autoinducer signaling molecule (N-3-oxohexanoyl homoserine lactone) is recognized and bound by the activator protein LuxR.
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