Results 1 to 10 of about 8,250 (60)

The prognostic value of clinical frailty scale and outcomes in older patients undergoing left ventricular assist device implantation

open access: yesAGING MEDICINE, Volume 5, Issue 4, Page 257-263, December 2022., 2022
The main finding in our study is that Clinical Frailty Scale‐defined frailty status was predictive of 1‐year post‐interventional mortality after left ventricular assist device implantation. Abstract Objectives Heart failure impacts patients’ functional capabilities, ultimately leading to frailty.
Temitope Ajibawo   +3 more
wiley   +1 more source

The tacrolimus concentration‐to‐dose ratio is associated with kidney function in heart transplant recipients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Heart transplantation (HT) is frequently complicated by chronic kidney disease, of which tacrolimus‐related nephrotoxicity is an important cause. In kidney and liver transplant recipients, fast tacrolimus metabolism (defined as a low concentration‐to‐dose [C0/D] ratio), negatively affects kidney function.
Maaike R. Schagen   +9 more
wiley   +1 more source

In heart failure, echocardiographic parameters of right ventricular function are powerful tools to predict renal failure

open access: yesESC Heart Failure, EarlyView.
Abstract Background Chronic kidney disease (CKD) has a high prevalence in patients with heart failure (HF) and is associated with prolonged hospitalization, increased need for intensive care and mortality. There is an urgent need to identify factors that influence the interaction between heart and kidney disorders, often described as cardiorenal ...
Alexander Reinecke   +7 more
wiley   +1 more source

Long‐term outcomes of apixaban as main anticoagulant in patients with HeartMate 3 left ventricular assist devices

open access: yesESC Heart Failure, EarlyView.
Abstract Aims HeartMate 3 (HM3) left ventricular assist devices (LVADs) offer improved haemocompatibility‐related outcomes for end‐stage heart failure patients, facilitating the exploration of alternative anticoagulation therapies beyond warfarin.
Jennifer Jdaidani   +7 more
wiley   +1 more source

Guideline‐directed medical therapy rates in heart failure patients with reduced ejection fraction in a diverse cohort

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Guideline‐directed medical therapy (GDMT) is recommended for all patients with heart failure with reduced ejection fraction (HFrEF). Despite this, little data exist describing GDMT use in diverse, real‐world populations including the use of vasodilators, prescribed primarily to Black populations.
Natalia C. Berry   +4 more
wiley   +1 more source

Exercise‐induced dynamic mitral regurgitation is associated with outcomes in patients with ischaemic cardiomyopathy

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Ischaemic mitral regurgitation (MR) is a dynamic condition influenced by global and regional left ventricular remodelling as well as mitral valvular deformation. Exercise testing plays a substantial role in assessing the haemodynamic relevance of MR and is recommended by current guidelines.
Maximilian Spieker   +14 more
wiley   +1 more source

Predicting right ventricular failure after left ventricular assist device implant: A novel approach

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Right ventricular (RV) failure (RVF) after left ventricular assist device (LVAD) implant is an important cause of morbidity and mortality. Modern, data‐driven approaches for defining and predicting RVF have been under‐utilized. Methods Two hundred thirty‐two patients were identified with a mean age of 55 years; 40 (17%) were women, 132 ...
Carissa E. Livingston   +6 more
wiley   +1 more source

Validation of a biomarker‐based mortality score for cardiogenic shock patients: Comparison with a clinical risk score

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Cardiogenic shock (CS) is the deadliest manifestation of acute heart failure, with persistently high mortality rates and a lack of recent therapeutic breakthroughs. Accurate risk prediction is crucial in clinical decision‐making and the design of future clinical trials.
Elina Hynninen   +14 more
wiley   +1 more source

Right ventricular dysfunction for prediction of long‐term recovery in de novo HFrEF : a PROLONG‐II substudy

open access: yesESC Heart Failure, EarlyView.
Abstract Aims To analyse the predictive value of advanced markers of right ventricular (RV) function and RV‐pulmonary arterial (PA) coupling in forecasting long‐term left ventricular (LV) improvement in de novo heart failure with reduced ejection fraction (HFrEF).
Aiste Monika Jakstaite   +10 more
wiley   +1 more source

Electron microscopic findings predict clinical outcomes in patients with non‐ischaemic cardiomyopathy

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Electron microscopy reveals microstructural alterations in cardiomyocyte nuclei and myofilaments in non‐ischaemic cardiomyopathy (NICM), particularly in dilated cardiomyopathy (DCM). Nevertheless, the correlation between such observations and clinical outcomes, including prognosis and left ventricular reverse remodelling (LVRR), remains ...
Rie Higuchi   +19 more
wiley   +1 more source

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