Results 91 to 100 of about 15,817 (237)

Longer Baseline Left Ventricular Activation Time Is Associated With Lower Mortality and Lower Risk of Heart Failure Hospitalization in Cardiac Resynchronization Therapy Recipients

Annals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.
In patients undergoing CRT implantation, a longer pre‐implant LVAT was linked to better clinical outcome (lower risk of heart failure hospitalization and all‐cause mortality), suggesting that LVAT may help refine risk stratification after CRT. ABSTRACT Introduction Many patients do not benefit from cardiac resynchronization therapy (CRT) with current ...
Sofia Marinko, Pyotr G. Platonov, Rasmus Borgquist   +2 more
wiley   +1 more source

LVAD Driveline Infection Readmission: Prevention by Standardization

, 2018
Recurrent driveline infection is the most common readmission diagnosis for patients after being implanted with an LVAD. The literature shows that readmission on post LVAD implantation on average costs $35,000.
Goodwin, Casey, Busorguina, Olga, Conley, Sean   +2 more
core   +1 more source

Computational analysis of the hemodynamic characteristics under interaction influence of β-blocker and LVAD

BioMedical Engineering OnLine, 2018
Background Hemodynamic characteristics of the interaction influence among support level and model of LVAD, and coupling β-blocker has not been reported.
Kaiyun Gu, Zhe Zhang, Yu Chang, Bin Gao, Feng Wan   +4 more
doaj   +1 more source

RRAGD p.(Ser76Leu) Variant Causes Dysregulated Expression of Muscle Development and Cytoskeleton Genes in Cardiomyocytes

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Under normal conditions, RagD and mTORC1 respond to amino acid changes. Upon stimulation, active mTORC1 phosphorylates S6K, 4E‐BP1, and TFEB. In response to starvation, mTORC1 is inactive. Our data indicate that the RRAGD p.(Ser76Leu) variant maintains the phosphorylation of mTORC1 targets during starvation in T‐REx HeLa cells.
Anastasia Adella, Sara B. van Katwijk, Pieter A. Leermakers, Willem B. van Ham, Hesther de Ruiter, Judita Ilgutytė, Suzanne Hendrickx, Levi Nijland, Teun P. de Boer, Eva van Rooij, Joost G. J. Hoenderop, Jeroen H. F. de Baaij   +11 more
wiley   +1 more source

Coronary Blood Flow Dynamics During Continuous Flow Left Ventricular Assist Device Support: Insights From a Virtual Cohort and In‐Silico Simulations

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
A virtual HeartMate 3 patient cohort was generated to analyze how cardiac, coronary, and regulatory parameters influence left and right coronary blood flow using an in‐silico experimentation framework. Results showed left coronary flow is mainly shaped by regulatory mechanisms, whereas right coronary flow depends strongly on CF‐LVAD speed, ventricular ...
Selim Bozkurt
wiley   +1 more source

Recent change in bridging strategy and improved clinical outcomes following durable left ventricular assist device implantation in Japan

JHLT Open
Background: Destination therapy (DT) was approved in Japan in May 2021. Use of Impella device as a bridge to left ventricular assist device (LVAD) implantation has been increasing.
Makiko Nakamura, Teruhiko Imamura, Yoshikatsu Saiki, Minoru Ono, Koichiro Kinugawa   +4 more
doaj   +1 more source

Does Gastrointestinal Bleeding Increase the Risk of Thromboembolic Events in Patients Supported With CF‐LVADs?

Artificial Organs, Volume 50, Issue 6, Page 886-890, June 2026.
Gastrointestinal bleeding significantly increases thromboembolic risk. Higher risk was also seen in patients aged ≥ 50 years, Black patients, and those with older CF‐LVAD models. ABSTRACT Background Gastrointestinal bleeding is a common complication in continuous‐flow left ventricular assist device (CF‐LVAD) patients. Managing gastrointestinal bleeding
Anh Nguyen, Alexis Shafii, Gabriel Loor, Subhasis Chatterjee, Andrew Civitello, O. Howard Frazier, Kenneth Liao   +6 more
wiley   +1 more source

Cold Atmospheric Plasma Therapy: An Innovative Approach to Treating Driveline Infections in Left Ventricular Assist Device Recipients

Artificial Organs, Volume 50, Issue 6, Page 877-885, June 2026.
Cold atmospheric plasma therapy is an innovative approach to treating driveline infections in left ventricular assist device (LVAD) patients. It provides a safe, contact‐free, and quick treatment option for driveline infections with significant improvement in LVAD patient outcomes and quality of life.
Hebe Al Asadi, Martina Socha, Christiane Marko, Delphine Vanilla Cioffi, Roxana Moayedifar, Julia Riebandt, Daniel Zimpfer, Thomas Schlöglhofer   +7 more
wiley   +1 more source

Patients’ average LVAD waveform responses.

, 2020
Overview of the three average responses from patients’ LVAD pump flow at rest and during exercise. Parameter values for the responses are depicted in Table 3.
Libera Fresiello (4268050), Heinrich Schima (8043344), Christiane Marko (8595759), Christoph Gross (8595750), Dominik Wiedemann (388586), Francesco Moscato (8413617), Martin Maw (8595762), Thomas Schlöglhofer (8595753), Kamen Dimitrov (8595756), Daniel Zimpfer (7900883), Bart Meyns (4268044)   +10 more
core   +1 more source

Higher sensitivity to ouabain‐induced toxicity in human induced pluripotent stem cell‐derived cardiomyocytes than human adult heart tissue despite similar Na+/K+‐ATPase pump current amplitudes

British Journal of Pharmacology, Volume 183, Issue 11, Page 3093-3110, June 2026.
Abstract Background and Purpose Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CM) have gained interest as a pharmacological model but their immaturity leads to uncertainty regarding translation. We studied the key player in maintaining ionic homeostasis, the Na+/K+‐ATPase (NKA), in hiPSC‐CM.
Djemail Ismaili, Paavo Virtanen, Junsoo Im, Paul Brunnbauer, Umber Saleem, Muhammed Ikbal Sönmez, Carl Schulz, Margaret Nandudu, Joris Winters, Cristina E. Molina, Johannes Petersen, Monika Stoll, Ulrich Schotten, Arne Hansen, Thomas Eschenhagen, Jussi T. Koivumäki, Torsten Christ   +16 more
wiley   +1 more source