Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury. [PDF]
Animal studies have demonstrated beneficial effects of therapeutic hypothermia on myocardial function, yet exact mechanisms remain unclear. Impaired autophagy leads to heart failure and mitophagy is important for mitigating ischemia/reperfusion injury ...
Andres, Allen M +10 more
core
Longer right to left ventricular activation delay at cardiac resynchronization therapy implantation is associated with improved clinical outcome in left bundle branch block patients. [PDF]
AIMS: Data on longer right to left ventricular activation delay (RV-LV AD) predicting clinical outcome after cardiac resynchronization therapy (CRT) by left bundle branch block (LBBB) are limited.
Gellér, László Alajos +8 more
core +1 more source
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson +11 more
wiley +1 more source
Background: The HeartMate 3 (HM3) has become among the most widely utilized durable left ventricular (LV) assist devices (LVAD) owing to reduced rates of pump thrombosis, bleeding, and stroke.
Ryaan EL-Andari, MD +10 more
doaj +1 more source
Left Ventricular Assist Devices (LVADS): History, Clinical Application and Complications [PDF]
Howard J. Eisen
openalex +1 more source
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley +1 more source
Mechanical circulatory support for destination therapy. [PDF]
Patients with chronic heart failure who are not eligible for heart transplant and whose life expectancy depends mainly on the heart disease may benefit from mechanical circulatory support.
Hullin, R., Tozzi, P.
core +1 more source
Alternative Measures of Body Composition and Outcomes Following Heart Transplant
ABSTRACT Current guidelines for heart transplant (HT) listing support body mass index (BMI) < 35 kg/m2, though data supporting this recommendation is mixed. It is unclear if other more specific measurements of body composition are better predictors of outcomes post‐HT.
Ana Lanier +17 more
wiley +1 more source
Ablation therapy for ventricular arrhythmias in patients with LVAD: Multiple faces of an electrophysiological challenge [PDF]
Nicolò Sisti +7 more
openalex +1 more source
Cutting the Cord: A Case of Late Presenting Driveline Infection [PDF]
Ventricular assist device (VAD) related infection, specifically driveline infection, is a common complication after VAD implantation. A 45-year old patient with a delayed skin infection at the site of the original driveline nearly one year after VAD ...
Eyadiel, Lauren +2 more
core +1 more source

