On the Kinetics of Human Skin Mast Cell Depletion and Repopulation Following KIT Inhibition. [PDF]
Allergy, Volume 81, Issue 2, Page 598-600, February 2026.
Alvarado D +11 more
europepmc +2 more sources
Voices from the Community: New insights into costs of dementia from persons with lived experience, public health leaders and health care providers [PDF]
Abstract Background The economic impact of dementia on individuals, families, communities, systems, and societies has not been fully assessed for integration into estimates of dementia costs. Through a joint effort of the University of Southern California and the Alzheimer's Association, a Family and Persons Living with Dementia (FPLWD) Panel and a ...
Neumann L +6 more
europepmc +2 more sources
Externally‐Led Patient‐Focused Drug Development Meeting (EL‐PFDD) for Dementia with Lewy Bodies—DLB: Voices of Lived Experience on Life with Lewy and Unmet Treatment Needs [PDF]
Abstract Background Dementia with Lewy bodies (DLB) is a prevalent form of dementia associated with neuronal alpha‐synuclein aggregates (Lewy bodies). Symptoms include cognitive impairment, fluctuations, neuropsychiatric features including psychosis, sleep disorders, and dysautonomia.
Fargo K +17 more
europepmc +2 more sources
Association of neighborhood deprivation with Alzheimer's Disease pathologies, gray matter volume, white matter hyperintensities and cognition by sex, race or ethnicity and APOE4 status in Non‐demented Older Adults [PDF]
Abstract Background Neighborhood socio‐economic conditions may increase Alzheimer's disease (AD) risk through amyloid, tau, atrophy or vascular pathways, potentially varying by genetic risk, race or ethnicity and sex. We examined associations between Area Deprivation Index (ADI) and cognition, AD pathology, gray matter (GM) and white matter ...
Aguilar P +8 more
europepmc +2 more sources
Association of neighborhood social and built environment with physical activity in U.S. POINTER [PDF]
Abstract Background Neighborhood social and built environment characteristics may promote physical activity, a modifiable factor for dementia risk, which may in turn promote cognitive and brain health. We explored the associations of the U.S. National Walkability Index ‐ a nationwide geographic data resource that ranks block groups according to their ...
Aguilar P +12 more
europepmc +2 more sources
Sociodemographic associations with AD biomarkers in POINTER, UBRAIN, and ADNI [PDF]
Abstract Background In aging and dementia research, the relationships between modifiable risk factors and biomarkers often vary across cohorts. We aim to evaluate the consistency and generalizability of the association between the area deprivation index (ADI) ‐ an indicator of socioeconomic/resource disadvantage within a specific area ‐ and cognition ...
Aguilar P +21 more
europepmc +2 more sources
Development and preliminary findings of a scoping review on the use of real‐world data in health services research for Alzheimer’s disease and related dementias [PDF]
Abstract Background The Alzheimer’s Association has prioritized advancing health services research (HSR) to improve care and outcomes for people living with Alzheimer’s disease and related dementias (AD/ADRD). HSR plays a critical role in investigating how care and treatment for AD/ADRD are accessed, delivered, and experienced.
Kuzmik A +7 more
europepmc +2 more sources
Blood-based biomarkers for detecting Alzheimer's disease pathology in cognitively impaired individuals within specialized care settings: A systematic review and meta-analysis. [PDF]
Abstract BACKGROUND This systematic review and meta‐analysis aimed to assess the diagnostic test accuracy of blood‐based biomarkers (BBMs) for detecting Alzheimer's disease (AD) pathology in cognitively impaired individuals in specialized care settings.
Pahlke S +19 more
europepmc +2 more sources
Efficacy and safety of vutrisiran in transthyretin amyloid cardiomyopathy across the age spectrum: The HELIOS-B trial. [PDF]
Summary of the HELIOS‐B trial design. Right: Forest (top) and spline (bottom) plots demonstrating the effect of vutrisiran versus placebo on clinical outcomes across age groups in HELIOS‐B. Age‐stratified outcomes with vutrisiran in transthyretin amyloid cardiomyopathy.
Sheikh A +8 more
europepmc +2 more sources
The alleged intermission in the coin production of Eastern and Central Lycia after the establish-ment of the so-called “dynasty of Xanthos” in Western Lycia during the thirties of the 5th century BC is to be filled with the coinage of Teththiweibi, the ...
Wilhelm Müseler
doaj +1 more source

