Results 71 to 80 of about 3,273 (139)

Borrelia and Genital Lichen Sclerosus: A Critical Review of the Evidence

JEADV Clinical Practice, Volume 5, Issue 3, Page 777-785, September 2026.
We reviewed the evidence linking Borrelia as an aetiological factor to LSc. Thirty‐six studies were included. No significant differences in Borrelia detection were observed between LSc and comparator dermatoses using ELISA, PCR, culture, or microscopy. A significant difference observed with IHC was considered an outlier.
Liang Zhi Wong, Richard Watchorn, Sandra Jerkovic Gulin, Christopher B. Bunker, Georgios Kravvas   +4 more
wiley   +1 more source

Differentiating Peromyscus leucopus bone marrow-derived macrophages for characterization of responses to Borrelia burgdorferi and lipopolysaccharide

Infection and Immunity
Currently, most tools utilized in host-pathogen interaction studies depend on the use of human or mouse (Mus musculus) cells and tissues. While these species have led to countless breakthroughs in our understanding of infectious disease, there are ...
Christopher C. Wells, Tanja Petnicki-Ocwieja, Shumin Tan, Stephen C. Bunnell, Sam R. Telford, Linden T. Hu, Jeffrey S. Bourgeois   +6 more
doaj   +1 more source

Characterizing Combined Central and Peripheral Demyelination—Insights From a Multimodal Comparison With Chronic Inflammatory Demyelinating Polyneuropathy and Multiple Sclerosis

Muscle &Nerve, Volume 74, Issue 3, Page 605-615, September 2026.
ABSTRACT Introduction/Aims Combined central and peripheral demyelination (CCPD) is a rare dysimmune disorder sharing features with multiple sclerosis (MS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Direct comparisons of central and peripheral diagnostic findings across these entities remain limited. We, therefore, performed a
N. Dubuisson, A. Kassab, P. Y. K. Van den Bergh, A. F. J. E. Vrancken, W. L. van der Pol, L. H. van den Berg, H. S. Goedee   +6 more
wiley   +1 more source

Serial FDG‐PET in probable seronegative autoimmune encephalitis presenting as severe behavioral regression in a child with autism

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.
Abstract Background Autoimmune encephalitis in children may present with predominant psychiatric and behavioral symptoms, creating diagnostic challenges, particularly in patients with pre‐existing autism spectrum disorder. Seronegative forms are especially difficult to recognize because neuronal autoantibodies are not detected, and diagnostic ...
Edouard Guez, Theodore Falempin, Cyril Hanin, Alison Arbouche, Rony Boucher, Myriam Hamdi, Marie Raffin, Angèle Consoli, Aurélie Kas, Marianna Giannitelli, David Cohen   +10 more
wiley   +1 more source

Exploring user experiences of the National Institute of Health and Care Excellence’s Shared Decision Making learning package: an online qualitative study

BMJ Open
Objective To evaluate the user experience of the joint National Institute of Health and Care Excellence (NICE)/Keele University Shared Decision Making (SDM) learning package.Design A qualitative study using online semistructured interviews.
Jonathan Underhill, Neal Maskrey, Simon Jacklin, Jessica Thompson, Andy Hutchinson, Katie Maddock, Laura Norburn   +6 more
doaj   +1 more source

Lyme hastalığı

Journal of Experimental and Clinical Medicine, 2013
Kuzey yarım kürede en sık görülen zoonotik hastalıklardan biri olan Lyme hastalığı, spiroketlerin neden olduğu ve vücutta birden çok sistemi tutabilen bir hastalıktır. Kuzey Amerika’da hastalığa Borrelia burgdorferi neden olurken kuzey yarım kürenin diğer bölgelerinde farklı Borrelia türleri hastalık etkeni olabilmektedir.
YEMİŞ, Mücahit, METE, Bilgul, BALKAN, İlker   +2 more
openaire   +3 more sources

A cofactor‐promiscuous HMGR from the Lyme disease pathogen illuminates diversity in bacterial isoprenoid biosynthesis

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The Lyme disease pathogen Borrelia burgdorferi contains a highly reduced genome lacking many primary metabolic pathways. However, B. burgdorferi retains the mevalonate pathway that synthesizes isopentenyl pyrophosphate (IPP), the precursor to the peptidoglycan carrier lipid.
Isaac A. Paddy, Joshua McCausland, Madelyn Frazier, Poulami Chatterjee, Mekedlawit Setegne, Oliv Eidam, Christine Jacobs‐Wagner, Laura M. K. Dassama   +7 more
wiley   +1 more source

Lyme arthritis

Biomedicine & Pharmacotherapy, 1989
Evanescent arthralgias and myalgias are common early symptoms of Lyme disease. Transient, intermittent episodes of monoarticular, oligoarticular, or sometimes migratory polyarticular arthritis, lasting weeks to months, with disease-free intervals, are frequently observed in untreated patients with erythema chronicum migrans.
A, Kahan, B, Amor, C J, Menkes
openaire   +2 more sources

Twenty‐one questions shaping the future of plant phenology research in the 21st century

Functional Ecology, Volume 40, Issue 9, Page 2777-2792, September 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract This Perspective examines the critical frontiers shaping the future of plant phenology research and identifies key emerging challenges and opportunities expected to influence the field in the 21st century.
Barbara Templ, Johanna Kauffert, José A. Oteros, Sebastian Lehner, Eike Luedeling, Ester Prat, Victor Van der Meersch, Anton Vrieling, Jorad de Vries, Emma Izquierdo‐Verdiguier, Inaki García de Cortázar‐Atauri, Keke Duan, Urša Vilhar, Herminia Garcia‐Mozo, Francois Rebaudo, Haiyin Ye, Gal Oblišar, Raul Zurita‐Milla, Mahdi Khodadadzadeh, Annette Menzel   +19 more
wiley   +1 more source

Gene-based therapies for hemophilia

Research and Practice in Thrombosis and Haemostasis
Gene therapy is a transformative approach to treating genetic disorders in order to improve disease outcomes for patients. Hemophilia A and B are inherited genetic disorders caused by mutations in the FVIII and FIX genes, respectively.
Melissa F. Glasner, Steven Pipe, Wolfgang Miesbach   +2 more
doaj   +1 more source