Results 71 to 80 of about 40,823 (182)

Atorvastatin‐Associated Severe Bradyarrhythmia Following Multiorgan Dysfunction: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Statins are the primary treatment for hypercholesterolemia and a cornerstone of atherosclerotic cardiovascular disease prevention. Although generally safe, serious adverse effects may occur in selected patients, particularly when statins are used at high doses or without medical supervision.
Xiao‐Qing Kou, Yan‐Zhen Wang, Yi‐Rong Gan, Yun‐Long Zhang, Shu‐Yun He, Zheng Zhang   +5 more
wiley   +1 more source

Exploring user experiences of the National Institute of Health and Care Excellence’s Shared Decision Making learning package: an online qualitative study

BMJ Open
Objective To evaluate the user experience of the joint National Institute of Health and Care Excellence (NICE)/Keele University Shared Decision Making (SDM) learning package.Design A qualitative study using online semistructured interviews.
Jonathan Underhill, Neal Maskrey, Simon Jacklin, Jessica Thompson, Andy Hutchinson, Katie Maddock, Laura Norburn   +6 more
doaj   +1 more source

Untreated Psychosis and Healthcare‐Seeking Behaviour in Pakistan: A Qualitative Study With Young People, Carers, Traditional Healers, and Healthcare Professionals

Early Intervention in Psychiatry, Volume 20, Issue 8, August 2026.
ABSTRACT Background Prolonged delay between the onset of the first episode of psychosis (FEP) and initiation of treatment is common in lower‐ and middle‐income countries (LMICs), including Pakistan. This qualitative study explored perspectives of young persons with FEP, carers, healthcare professionals, and traditional and spiritual healers (TSHs) on ...
Noor Sanauddin, Lisa Dikomitis, Abdul Jalil Khan, Mian Mukhtar ul Haq Azeemi, Muhammad Firaz Khan, Saima Sheikh, Nishani Fonseka, Abbie Milner, Syed Muhammad Uzair Shah, Ishfaq Tariq Azeemi, Shumaila Hamid, Syeda Fatima Jamal, Aimee Sargeant, Saeed Farooq   +13 more
wiley   +1 more source

Machine Learning of Personal Repertoires From Public T Cell Receptors

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT The T‐cell receptor (TCR) repertoire records an individual's immunological history, but most unique CDR3 sequences in any one person are private and uninformative about anyone else. A small subset, however, recurs predictably across unrelated donors.
Or Malca, Alona Zilberberg, Sol Efroni
wiley   +1 more source

Gene-based therapies for hemophilia

Research and Practice in Thrombosis and Haemostasis
Gene therapy is a transformative approach to treating genetic disorders in order to improve disease outcomes for patients. Hemophilia A and B are inherited genetic disorders caused by mutations in the FVIII and FIX genes, respectively.
Melissa F. Glasner, Steven Pipe, Wolfgang Miesbach   +2 more
doaj   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Riboflavin Salvage Supports Glycolysis in Borrelia burgdorferi Through Flavin‐Dependent NAD+ Regeneration

Molecular Microbiology, Volume 126, Issue 2, Page 208-219, August 2026.
The Lyme disease agent Borrelia burgdorferi has limited metabolic capabilities and depends on salvage of riboflavin via the BB0316‐BB0319 transport system for generation of critical flavin cofactors FMN and FAD. Riboflavin is important for NAD+ regeneration to fuel glycolysis.
Anna M. Schulz, Grace E. Easterling, Aaditya Balasubramaniyan, Mollie W. Jewett   +3 more
wiley   +1 more source

Detecting Borrelia burgdorferi–Triggered Seronegative Rheumatoid Arthritis Using [68Ga]Ga‐DOTA–Siglec‐9–Positron Emission Tomography/Computed Tomography

ACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Prince Dadson, Heli Ylä‐Outinen, Simona Malaspina, Mikko Koivumäki, Sirpa Jalkanen, Laura Pirilä, Anne Roivainen   +6 more
wiley   +1 more source

Mapping the distribution of Lyme disease at a mid-Atlantic site in the United States using electronic health data.

PLoS ONE
Lyme disease is a spatially heterogeneous tick-borne infection, with approximately 85% of US cases concentrated in the mid-Atlantic and northeastern states. Surveillance for Lyme disease and its causative agent, including public health case reporting and
Paul M Lantos, Mark Janko, Lise E Nigrovic, Felicia Ruffin, Takaaki Kobayashi, Yvonne Higgins, Paul G Auwaerter   +6 more
doaj   +1 more source

Physician reported incidence of early and late Lyme borreliosis

Parasites & Vectors, 2015
Background Lyme borreliosis is the most common vector-borne disease in Europe and North America. The objective of this study is to estimate the incidence of tick bites and Lyme borreliosis, representative of our entire country, including erythema migrans,
Agnetha Hofhuis, Margriet Harms, Sita Bennema, Cees C van den Wijngaard, Wilfrid van Pelt   +4 more
doaj   +1 more source