Results 71 to 80 of about 2,831 (197)

Lyme neuroborreliosis in Japan: Borrelia burgdorferi sensu lato as a cause of meningitis of previously undetermined etiology in hospitalized patients outside of the island of Hokkaido, 2010–2021

European Journal of Neurology, Volume 32, Issue 1, January 2025.
Abstract Background and Purpose Clinical manifestations of Lyme borreliosis (LB), caused by Borrelia burgdorferi sensu lato (Bbsl), include erythema migrans, Lyme neuroborreliosis (LNB), carditis, and arthritis. LB is a notifiable disease in Japan with <30 surveillance‐reported LB cases annually, predominately from Hokkaido Prefecture.
Masayuki Ohira, Ai Takano, Kentaro Yoshi, Akira Arai, Yashuhiro Aso, Rikiya Furutani, Tadanori Hamano, Ikuko Takahashi‐Iwata, Chikako Kaneko, Tohru Matsuura, Norihisa Maeda, Hideto Nakajima, Katsuro Shindo, Toshihiko Suenaga, Kazuma Sugie, Yasuhiro Suzuki, Toru Yamashita, Frederick J. Angulo, Juanita Edwards, Cody Matthew Bender, Lisa R. Harper, Yoshikazu Nakayama, Shuhei Ito, Andreas Pilz, James H. Stark, Jennifer C. Moïsi, Hidehiro Mizusawa, Masaki Takao   +27 more
wiley   +1 more source

Intra-hisian 2:1 atrioventricular block secondary to Lyme disease [PDF]

, 2017
We describe a case of Lyme carditis with intra-hisian 2:1 atrioventricular (AV) block documented by electrophysiological study. To our knowledge, only two cases of AV block at the level of the His bundle has been described in the literature. Sinus rhythm
Adamec, R., de Freudenreich, J., Fleisch, M., Rey, M.-J, Viquerat, C., Zimmermann, M.   +5 more
core  

Mesenchymal Stem Cells Reduce Inflammation in a Mouse Model of Lyme Arthritis

Stem Cells International, Volume 2025, Issue 1, 2025.
Lyme disease (LD), a zoonotic infectious disease caused by Borrelia burgdorferi (B. burgdorferi), can affect various organs, including the skin, heart, nervous system, and joints. Lyme arthritis (LA) is the most common and severe late‐stage presentation of LD, often presenting with intermittent joint swelling and pain.
Weijiang Ma, Jing Kong, Mengqin Zhang, Hanxin Wu, Shanshan Wan, Xin Liu, Bingxue Li, Yan Dong, Lei Zhong, Weijie Ma, Li Gao, Xinya Wu, Li Peng, Suyi Luo, Zhenhua Ji, Yuxin Fan, Jingjing Chen, Meixiao Liu, Liangyu Zhu, Xun Huang, Rui Yang, Jieqin Song, Fukai Bao, Aihua Liu, Zhao-Jun Liu   +24 more
wiley   +1 more source

T cells exacerbate Lyme borreliosis in TLR2-deficient mice

Frontiers in Immunology, 2016
Infection of humans with the spirochete, Borrelia burgdorferi, causes Lyme borreliosis and can lead to clinical manifestations such as, arthritis, carditis and neurological conditions.
Carrie E. Lasky, Carmela Louise Pratt, Kinsey A Hilliard, Jacob J Jones, Charles Robert Brown   +4 more
doaj   +1 more source

DNA lipid nanoparticle vaccine targeting outer surface protein C affords protection against homologous Borrelia burgdorferi needle challenge in mice

Frontiers in Immunology, 2023
IntroductionThe incidence of Lyme disease (LD) in Canada and the United States has risen over the last decade, nearing 480,000 cases each year. Borrelia burgdorferi sensu lato, the causative agent of LD, is transmitted to humans through the bite of an ...
Annabelle Pfeifle, Annabelle Pfeifle, Sathya N. Thulasi Raman, Casey Lansdell, Wanyue Zhang, Wanyue Zhang, Levi Tamming, Levi Tamming, Jonathon Cecillon, Emmanuel Laryea, Devina Patel, Jianguo Wu, Caroline Gravel, Grant Frahm, Jun Gao, Jun Gao, Wangxue Chen, George Chaconas, Simon Sauve, Michael Rosu-Myles, Michael Rosu-Myles, Lisheng Wang, Michael J. W. Johnston, Michael J. W. Johnston, Xuguang Li, Xuguang Li   +25 more
doaj   +1 more source

Bridging the gap: Insights in the immunopathology of Lyme borreliosis

European Journal of Immunology, Volume 54, Issue 12, December 2024.
Lyme borreliosis is caused by Borrelia burgdorferi sensu lato transmitted by Ixodes ticks. The disease progresses from early localized infection to more severe conditions driven by ongoing inflammation. Understanding the role of Th1/Th2 balance, B‐cell dysfunction, and autoimmunity in Lyme borreliosis pathogenesis could improve diagnosis and treatment ...
Marijn E. Snik, Noor E.I.M. Stouthamer, Joppe W. Hovius, Melissa M.J. van Gool   +3 more
wiley   +1 more source

First case report of inducible heart block in Lyme disease and an update of Lyme carditis

BMC Infectious Diseases, 2019
Background Lyme disease (LD), is the most common vector-borne illness in the US and Europe, with predominantly cutaneous, articular, cardiac and neuro-psychiatric manifestations. LD affects all layers of the heart and every part of the conducting system.
Don Walter Kannangara, Sindhu Sidra, Patel Pritiben   +2 more
doaj   +1 more source

Estimated incidence of symptomatic Lyme borreliosis cases in five southern coastal counties in Norway, 2022

APMIS, Volume 132, Issue 11, Page 832-842, November 2024.
Lyme borreliosis (LB), the most common tick‐borne disease in Europe, is endemic to southern coastal Norway. LB commonly presents as erythema migrans, which can disseminate, resulting in more severe disease such as Lyme neuroborreliosis or arthritis. In Norway, public health LB surveillance is conducted via mandatory reporting of laboratory‐confirmed ...
Emily Colby, Tor Molden, Julia Olsen, Patrick Kelly, Andreas Pilz, Kate Halsby, Gordon Brestrich, Frederick J. Angulo, Jennifer C. Moïsi, James H. Stark   +9 more
wiley   +1 more source

Racial and ethnic disparities in Lyme disease in the United States

Zoonoses and Public Health, Volume 71, Issue 5, Page 469-479, August 2024.
Abstract Introduction Lyme disease (LD), caused by the spirochete Borrelia burgdorferi, is the most common vector‐borne disease in the United States. Although most surveillance‐reported cases are in people who are White, data suggest worse outcomes among people from racial and ethnic minority groups.
L. Hannah Gould, Adam Fathalla, Jennifer C. Moïsi, James H. Stark   +3 more
wiley   +1 more source

Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex [PDF]

, 2016
Citation: Garcia, B. L., Zhi, H., Wager, B., Hook, M., & Skare, J. T. (2016). Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex. Plos Pathogens, 12(1), 28.
A Alitalo, A Hubner, A Roos, A Sadziene, A Sadziene, AE Davis 3rd, AG Barbour, AP van Dam, B Major, Beau Wager, BK Boardman, Brandon L. Garcia, BV Geisbrecht, C Gaboriaud, CA Brissette, CJ Hastey, CS Brooks, D Ricklin, D Ricklin, D. Scott Samuels, DS Samuels, E Fikrig, EA Rogers, EA Rogers, EH Weening, ER Lewis, G Harris, G Stanek, Girija U Venkatraman, H Zhi, Hui Zhi, I Bally, J Hellwage, J Pietikainen, J Schwab, J Seshu, JA Caine, JA Hyde, JD Lambris, JD Radolf, JH Kim, Jon T. Skare, JR Fischer, JV McDowell, JV McDowell, K Kurtenbach, KM Hovis, LK Bockenstedt, LY Lee, M Hammel, M He, M Jozsi, M Labandeira-Rey, M Pausa, Magnus Höök, MB Lawrenz, MC Carroll, MC Carroll, ME Woodman, MJ Caimano, MN Burtnick, MR Kenedy, MR Kenedy, MU Norman, NA Meenan, NM Thielens, P Kraiczy, P Kraiczy, PF Zipfel, R Wallis, RA Elsner, RA Gaultney, RJ Bingham, RJ Ziccardi, RJ Ziccardi, S Grosskinsky, S Prabhakaran, S Raibaud, S Thiel, SK Kochi, SW de Taeye, T Bykowski, T Hallstrom, T Hallstrom, T Meri, TF Busby, TJ Moriarty, U Schwarz-Linek, UK Laemmli, V Cook, WK Ip, WS Probert, WS Probert, WS Probert, X Li, X Yang, XF Yang, Y Wu, YP Ko, YP Ko, YP Lin, ZR Marjenberg   +101 more
core   +9 more sources