Results 91 to 100 of about 720,622 (316)

A Fully-Automated Pipeline for Detection and Segmentation of Liver Lesions and Pathological Lymph Nodes [PDF]

open access: yesarXiv, 2017
We propose a fully-automated method for accurate and robust detection and segmentation of potentially cancerous lesions found in the liver and in lymph nodes. The process is performed in three steps, including organ detection, lesion detection and lesion segmentation.
arxiv  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Transfer of locally synthesized cholesterol from intestinal wall to intestinal lymph

open access: yesJournal of Lipid Research, 1968
The cholesterol-fed rat subjected to cannulation of the intestinal lymph duct and injected with acetate-2-14C has been utilized for a study of the mechanism by which cholesterol synthesized in the intestinal wall gains access to the circulation.
Jean D. Wilson, Robert T. Reinke
doaj  

The Antigen Processing and Presentation Machinery in Lymphatic Endothelial Cells

open access: yesFrontiers in Immunology, 2019
Until a few years ago, lymphatic vessels and lymphatic endothelial cells (LEC) were viewed as part of a passive conduit for lymph and immune cells to reach lymph nodes (LN).
Laura Santambrogio   +2 more
doaj   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

CT Synthesis with Conditional Diffusion Models for Abdominal Lymph Node Segmentation [PDF]

open access: yesarXiv
Despite the significant success achieved by deep learning methods in medical image segmentation, researchers still struggle in the computer-aided diagnosis of abdominal lymph nodes due to the complex abdominal environment, small and indistinguishable lesions, and limited annotated data.
arxiv  

Establishment and biological characterization of radioresistant colorectal cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu   +10 more
wiley   +1 more source

Automatic breast cancer grading in lymph nodes using a deep neural network [PDF]

open access: yesarXiv, 2017
The progression of breast cancer can be quantified in lymph node whole-slide images (WSIs). We describe a novel method for effectively performing classification of whole-slide images and patient level breast cancer grading. Our method utilises a deep neural network.
arxiv  

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