Results 121 to 130 of about 1,582,733 (410)
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Evidence for a contribution by the intestinal wall to the serum cholesterol of the rat
Journal of Lipid Research, 1965 Rats were fed cholesterol in order to block hepatic cholesterol synthesis, and their intestinal lymph ducts were cannulated. Experiments with these rats showed that cholesterol synthesized in the intestinal wall enters into the circulating cholesterol ...
Charles A. Lindsey, Jr., Jean D. Wilson
doaj
RANK is essential for osteoclast and lymph node development.
Genes & Development, 1999 The physiological role of the TNF receptor (TNFR) family member, RANK, was investigated by generating RANK-deficient mice. RANK(-/-) mice were characterized by profound osteopetrosis resulting from an apparent block in osteoclast differentiation.
W. Dougall +17 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Physical and chemical changes in isolated chylomicrons: prevention by EDTA
Journal of Lipid Research, 1970 When washed chylomicrons obtained from the lymph of rats, which had been fed corn oil, were maintained at 0-4°C in 0.9% NaCl, the following physical and chemical changes were observed to occur: increased polarity of chylomicron lipids, increased ...
Joseph A. Ontko
doaj
Current Techniques for Detecting Sentinel Lymph Nodes in Vulvar Cancer
Креативная хирургия и онкология, 2019 Introduction. Vulvar cancer belongs to the group of rare neoplasms and accounts for about 4% of all gynecological malignant tumours. One of the important barriers to the spread of the tumour cell population is the lymph nodes.
Sh. Kh. Gantsev +2 more
doaj +1 more source
Comparison of machine learning methods for classifying mediastinal lymph node metastasis of non-small cell lung cancer from 18F-FDG PET/CT images [PDF]
, 2017 The present study shows that the performance of CNN is not significantly different from the best classical methods and human doctors for classifying mediastinal lymph node metastasis of NSCLC from PET/CT images. Because CNN does not need tumor segmentation or feature calculation, it is more convenient and more objective than the classical methods ...
arxiv +1 more source
DR-bearing T lymphocytes in thoracic duct lymph [PDF]
, 1981 T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks ...
Abo +25 more
core +1 more source
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source